1ZYQ

T7 DNA polymerase in complex with 8oG and incoming ddATP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	P	5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG))-3'	polymer	22	6764.4	1
2	T	5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3'	polymer	26	7939.1	1
3	A	DNA polymerase	polymer	698	79031.7	1	UniProt (P00581) Pfam (PF00476) In PDB	Enterobacteria phage T7	T7 DNA polymerase
4	B	Thioredoxin 1	polymer	108	11687.4	1	UniProt (P0AA25) Pfam (PF00085) In PDB	Escherichia coli	TRX1, TRX
5	A	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
6	A	2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE	non-polymer		475.2	1	Chemie (DAD)
7		water	water		18.0	219	Chemie (HOH)

Sequence modifications

A: 1 - 698 (UniProt: P00581)

PDB	External Database	Details
-	Lys 118	deletion
-	Arg 119	deletion
-	Phe 120	deletion
-	Gly 121	deletion
-	Ser 122	deletion
-	His 123	deletion
Ala 536	Lys 536	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	105422.5
Non-Polymers*	Number of molecules	4
	Total formula weight	548.1
All*	Total formula weight	105970.6

*Water molecules are not included.