7NVH
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![BU of 7nvh by Molmil](/molmil-images/mine/7nvh) | Cryo-EM structure of the mycolic acid transporter MmpL3 from M. tuberculosis | Descriptor: | Lauryl Maltose Neopentyl Glycol, Trehalose monomycolate exporter MmpL3 | Authors: | Adams, O, Deme, J.C, Parker, J.L, Lea, S.M, Newstead, S. | Deposit date: | 2021-03-15 | Release date: | 2021-06-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target. Structure, 29, 2021
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8FY3
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![BU of 8fy3 by Molmil](/molmil-images/mine/8fy3) | Structure of NOT1:NOT10:NOT11 module of the human CCR4-NOT complex | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | Authors: | Lea, S.M, Deme, J.C, Raisch, T, Pekovic, F, Valkov, E. | Deposit date: | 2023-01-25 | Release date: | 2023-07-26 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex. Commun Biol, 6, 2023
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8FY4
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![BU of 8fy4 by Molmil](/molmil-images/mine/8fy4) | Structure of NOT1:NOT10:NOT11 module of the chicken CCR4-NOT complex | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | Authors: | Lea, S.M, Deme, J.C, Raisch, T, Levdansky, Y, Valkov, E. | Deposit date: | 2023-01-25 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex. Commun Biol, 6, 2023
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7BC6
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![BU of 7bc6 by Molmil](/molmil-images/mine/7bc6) | Cryo-EM structure of the outward open proton coupled folate transporter at pH 7.5 | Descriptor: | Proton-coupled folate transporter, nanobody | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | Deposit date: | 2020-12-18 | Release date: | 2021-05-12 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of antifolate recognition and transport by PCFT. Nature, 595, 2021
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7BC7
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![BU of 7bc7 by Molmil](/molmil-images/mine/7bc7) | Cryo-EM structure of the proton coupled folate transporter at pH 6.0 bound to pemetrexed | Descriptor: | 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, Proton-coupled folate transporter, nanobody | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | Deposit date: | 2020-12-18 | Release date: | 2021-05-12 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of antifolate recognition and transport by PCFT. Nature, 595, 2021
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7AKV
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![BU of 7akv by Molmil](/molmil-images/mine/7akv) | The cryo-EM structure of the Vag8-C1 inhibitor complex | Descriptor: | Plasma protease C1 inhibitor, Vag8 | Authors: | Johnson, S, Lea, S.M, Deme, J.C, Furlong, E, Dhillon, A. | Deposit date: | 2020-10-02 | Release date: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex. Mbio, 12, 2021
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6X9O
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![BU of 6x9o by Molmil](/molmil-images/mine/6x9o) | High resolution cryoEM structure of huntingtin in complex with HAP40 | Descriptor: | 40-kDa huntingtin-associated protein, Huntingtin | Authors: | Harding, R.J, Deme, J.C, Lea, S.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2020-06-03 | Release date: | 2020-06-17 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1. Commun Biol, 4, 2021
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8SAH
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![BU of 8sah by Molmil](/molmil-images/mine/8sah) | Huntingtin C-HEAT domain in complex with HAP40 | Descriptor: | 40-kDa huntingtin-associated protein, Huntingtin | Authors: | Harding, R.J, Deme, J.C, Alteen, M.G, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC) | Deposit date: | 2023-03-31 | Release date: | 2023-04-26 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40. Structure, 31, 2023
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8SA2
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![BU of 8sa2 by Molmil](/molmil-images/mine/8sa2) | Adenosylcobalamin-bound riboswitch dimer, form 1 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 1 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA4
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![BU of 8sa4 by Molmil](/molmil-images/mine/8sa4) | Adenosylcobalamin-bound riboswitch dimer, form 3 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 3 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA3
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![BU of 8sa3 by Molmil](/molmil-images/mine/8sa3) | Adenosylcobalamin-bound riboswitch dimer, form 2 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 2 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA6
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![BU of 8sa6 by Molmil](/molmil-images/mine/8sa6) | apo form of adenosylcobalamin riboswitch dimer | Descriptor: | apo form of adenosylcobalamin riboswitch dimer | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (5.3 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA5
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![BU of 8sa5 by Molmil](/molmil-images/mine/8sa5) | Adenosylcobalamin-bound riboswitch dimer, form 4 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 4 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8UPL
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![BU of 8upl by Molmil](/molmil-images/mine/8upl) | Cryo-EM structure of a Clockwise locked form of the Salmonella enterica Typhimurium flagellar C-ring, with C34 symmetry applied | Descriptor: | Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ... | Authors: | Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2023-10-22 | Release date: | 2024-01-24 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Structural basis of directional switching by the bacterial flagellum. Nat Microbiol, 9, 2024
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8UOX
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![BU of 8uox by Molmil](/molmil-images/mine/8uox) | Cryo-EM structure of a Counterclockwise locked form of the Salmonella enterica Typhimurium flagellar C-ring, with C34 symmetry applied | Descriptor: | Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ... | Authors: | Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2023-10-20 | Release date: | 2024-01-24 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis of directional switching by the bacterial flagellum. Nat Microbiol, 9, 2024
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8UMD
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![BU of 8umd by Molmil](/molmil-images/mine/8umd) | Cryo-EM structure of a single subunit of a Counterclockwise-locked form of the Salmonella enterica Typhimurium flagellar C-ring. | Descriptor: | Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ... | Authors: | Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2023-10-17 | Release date: | 2024-01-24 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of directional switching by the bacterial flagellum. Nat Microbiol, 9, 2024
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8UMX
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![BU of 8umx by Molmil](/molmil-images/mine/8umx) | Cryo-EM structure of a single subunit of a Clockwise-locked form of the Salmonella enterica Typhimurium flagellar C-ring. | Descriptor: | Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ... | Authors: | Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2023-10-18 | Release date: | 2024-01-24 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of directional switching by the bacterial flagellum. Nat Microbiol, 9, 2024
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6S3R
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![BU of 6s3r by Molmil](/molmil-images/mine/6s3r) | Structure of the FliPQR complex from the flagellar type 3 secretion system of Pseudomonas savastanoi. | Descriptor: | Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2019-06-25 | Release date: | 2020-03-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion. Nat Commun, 11, 2020
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6SD1
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![BU of 6sd1 by Molmil](/molmil-images/mine/6sd1) | Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 33-fold symmetry applied | Descriptor: | Flagellar M-ring protein | Authors: | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | Deposit date: | 2019-07-26 | Release date: | 2020-03-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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6SCN
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![BU of 6scn by Molmil](/molmil-images/mine/6scn) | 33mer structure of the Salmonella flagella MS-ring protein FliF | Descriptor: | Flagellar M-ring protein | Authors: | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | Deposit date: | 2019-07-24 | Release date: | 2020-03-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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6SD3
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![BU of 6sd3 by Molmil](/molmil-images/mine/6sd3) | 34mer structure of the Salmonella flagella MS-ring protein FliF | Descriptor: | Flagellar M-ring protein | Authors: | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | Deposit date: | 2019-07-26 | Release date: | 2020-03-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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6SD2
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![BU of 6sd2 by Molmil](/molmil-images/mine/6sd2) | Structure of the RBM2inner region of the Salmonella flagella MS-ring protein FliF with 21-fold symmetry applied. | Descriptor: | Flagellar M-ring protein | Authors: | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | Deposit date: | 2019-07-26 | Release date: | 2020-03-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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6SD4
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![BU of 6sd4 by Molmil](/molmil-images/mine/6sd4) | Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 34-fold symmetry applied | Descriptor: | Flagellar M-ring protein | Authors: | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | Deposit date: | 2019-07-26 | Release date: | 2020-03-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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6SD5
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![BU of 6sd5 by Molmil](/molmil-images/mine/6sd5) | Structure of the RBM2 inner ring of Salmonella flagella MS-ring protein FliF with 22-fold symmetry applied | Descriptor: | Flagellar M-ring protein | Authors: | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | Deposit date: | 2019-07-26 | Release date: | 2020-03-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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6TRE
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![BU of 6tre by Molmil](/molmil-images/mine/6tre) | Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 32-fold symmetry applied | Descriptor: | Flagellar M-ring protein | Authors: | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | Deposit date: | 2019-12-18 | Release date: | 2020-03-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system. To Be Published
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