8JKN
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8JKO
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8JKL
| IRF4 DNA-binding domain bound to an DNA containing GATA motif | Descriptor: | GATA-Forward, GATA-Reverse, Interferon regulatory factor 4 | Authors: | Wang, G, Feng, X, Ding, J. | Deposit date: | 2023-06-01 | Release date: | 2023-09-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
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8JKQ
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8JKS
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2LMF
| Solution structure of human LL-23 bound to membrane-mimetic micelles | Descriptor: | Antibacterial protein LL-37 | Authors: | Wang, G. | Deposit date: | 2011-11-30 | Release date: | 2011-12-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure, Dynamics, and Antimicrobial and Immune Modulatory Activities of Human LL-23 and Its Single-Residue Variants Mutated on the Basis of Homologous Primate Cathelicidins. Biochemistry, 51, 2012
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2K6O
| Human LL-37 Structure | Descriptor: | Cathelicidin antimicrobial peptide | Authors: | Wang, G. | Deposit date: | 2008-07-14 | Release date: | 2008-09-23 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles J.Biol.Chem., 283, 2008
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2L5M
| Solution structure of GF-17 in complex with micelles | Descriptor: | GF-17 | Authors: | Wang, G. | Deposit date: | 2010-11-02 | Release date: | 2011-11-02 | Last modified: | 2012-02-29 | Method: | SOLUTION NMR | Cite: | Decoding the Functional Roles of Cationic Side Chains of the Major Antimicrobial Region of Human Cathelicidin LL-37. Antimicrob.Agents Chemother., 56, 2012
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1NH9
| Crystal Structure of a DNA Binding Protein Mja10b from the hyperthermophile Methanococcus jannaschii | Descriptor: | DNA-binding protein Alba | Authors: | Wang, G, Bartlam, M, Guo, R, Yang, H, Xue, H, Liu, Y, Huang, L, Rao, Z. | Deposit date: | 2002-12-19 | Release date: | 2003-12-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeon Methanococcus jannaschii Protein Sci., 12, 2003
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1VM2
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1VM4
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1VM3
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1VM5
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8DN0
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8EOC
| Crystal structure of E.coli DsbA mutant E24A/K58A | Descriptor: | COPPER (II) ION, GLYCEROL, Thiol:disulfide interchange protein DsbA | Authors: | Wang, G, Heras, B. | Deposit date: | 2022-10-03 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
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8EQQ
| Crystal structure of E.coli DsbA mutant E37A | Descriptor: | CITRATE ANION, Thiol:disulfide interchange protein DsbA | Authors: | Wang, G, Heras, B. | Deposit date: | 2022-10-09 | Release date: | 2023-02-15 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
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8EQO
| Crystal structure of E.coli DsbA mutant K58A | Descriptor: | COPPER (II) ION, GLYCEROL, Thiol:disulfide interchange protein DsbA | Authors: | Wang, G, Heras, B. | Deposit date: | 2022-10-08 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
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8EQP
| Crystal structure of E.coli DsbA mutant E24A/E37A/K58A | Descriptor: | CITRATE ANION, GLYCEROL, Thiol:disulfide interchange protein DsbA | Authors: | Wang, G, Heras, B. | Deposit date: | 2022-10-09 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
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8EQR
| Crystal structure of E.coli DsbA mutant E24A | Descriptor: | DI(HYDROXYETHYL)ETHER, Thiol:disulfide interchange protein DsbA | Authors: | Wang, G, Heras, B. | Deposit date: | 2022-10-09 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
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6PVZ
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6PVY
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6NM3
| NMR structure of WW295 | Descriptor: | WW295 peptide | Authors: | Wang, G, Zarena, D. | Deposit date: | 2019-01-10 | Release date: | 2020-07-15 | Last modified: | 2020-09-09 | Method: | SOLUTION NMR | Cite: | Two distinct amphipathic peptide antibiotics with systemic efficacy. Proc.Natl.Acad.Sci.USA, 117, 2020
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6NM2
| NMR Structure of WW291 | Descriptor: | WW291 peptide | Authors: | Wang, G, Zarena, D. | Deposit date: | 2019-01-10 | Release date: | 2020-07-15 | Last modified: | 2020-09-09 | Method: | SOLUTION NMR | Cite: | The pi Configuration of the WWW Motif of a Short Trp-Rich Peptide Is Critical for Targeting Bacterial Membranes, Disrupting Preformed Biofilms, and Killing Methicillin-Resistant Staphylococcus aureus. Biochemistry, 56, 2017
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1GGR
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6WHD
| Crystal structure of E.coli DsbA in complex with diaryl ether analogue 2 | Descriptor: | COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [4-(4-cyano-3-methylphenoxy)phenyl]acetic acid | Authors: | Wang, G, Heras, B. | Deposit date: | 2020-04-08 | Release date: | 2020-06-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX). J.Med.Chem., 63, 2020
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