2QUZ
 
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2E2X
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2D4Q
 | | Crystal structure of the Sec-PH domain of the human neurofibromatosis type 1 protein | | Descriptor: | Neurofibromin, OXTOXYNOL-10, PYROPHOSPHATE 2- | | Authors: | D'angelo, I, Welti, S, Bonneau, F, Scheffzek, K. | | Deposit date: | 2005-10-22 | | Release date: | 2006-03-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A novel bipartite phospholipid-binding module in the neurofibromatosis type 1 protein
Embo Rep., 7, 2006
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3CB6
 | | Crystal Structure of the S. pombe Peptidase Homology Domain of FACT complex subunit Spt16 (form B) | | Descriptor: | FACT complex subunit spt16 | | Authors: | Stuwe, T, Hothorn, M, Lejeune, E, Bortfeld-Miller, M, Scheffzek, K, Ladurner, A.G. | | Deposit date: | 2008-02-21 | | Release date: | 2008-06-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module
Proc.Natl.Acad.Sci.USA, 105, 2008
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3BXJ
 | | Crystal Structure of the C2-GAP Fragment of synGAP | | Descriptor: | Ras GTPase-activating protein SynGAP | | Authors: | Pena, V, Hothorn, M, Eberth, A, Kaschau, N, Parret, A, Gremer, L, Bonneau, F, Ahmadian, M.R, Scheffzek, K. | | Deposit date: | 2008-01-14 | | Release date: | 2008-03-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction.
Embo Rep., 9, 2008
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3CB5
 | | Crystal Structure of the S. pombe Peptidase Homology Domain of FACT complex subunit Spt16 (form A) | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FACT complex subunit spt16 | | Authors: | Stuwe, T, Hothorn, M, Lejeune, E, Bortfeld-Miller, M, Scheffzek, K, Ladurner, A.G. | | Deposit date: | 2008-02-21 | | Release date: | 2008-06-17 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module
Proc.Natl.Acad.Sci.USA, 105, 2008
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3G3Q
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3G3T
 | | Crystal structure of a eukaryotic polyphosphate polymerase in complex with orthophosphate | | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Vacuolar transporter chaperone 4 | | Authors: | Lenherr, E.D, Hothorn, M, Scheffzek, K. | | Deposit date: | 2009-02-02 | | Release date: | 2009-05-05 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase.
Science, 324, 2009
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3G3O
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8QVZ
 | | Human NDPK-C in complex with cAMP | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Nucleoside diphosphate kinase 3, SULFATE ION | | Authors: | Werten, S, Amjadi, R, Scheffzek, K. | | Deposit date: | 2023-10-18 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.774 Å) | | Cite: | Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes.
Int J Mol Sci, 25, 2024
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8QW1
 | | Human NDPK-C in complex with ADP and Mg2+ | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside diphosphate kinase 3 | | Authors: | Werten, S, Amjadi, R, Scheffzek, K. | | Deposit date: | 2023-10-18 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes.
Int J Mol Sci, 25, 2024
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8QW2
 | | Human NDPK-C in complex with UDP and Mg2+ | | Descriptor: | MAGNESIUM ION, Nucleoside diphosphate kinase 3, URIDINE-5'-DIPHOSPHATE | | Authors: | Werten, S, Amjadi, R, Scheffzek, K. | | Deposit date: | 2023-10-18 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes.
Int J Mol Sci, 25, 2024
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8QW0
 | | Human NDPK-C in complex with GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase 3, SULFATE ION | | Authors: | Werten, S, Amjadi, R, Scheffzek, K. | | Deposit date: | 2023-10-18 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.175 Å) | | Cite: | Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes.
Int J Mol Sci, 25, 2024
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8QW3
 | | Human NDPK-C in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase 3, SULFATE ION | | Authors: | Werten, S, Amjadi, R, Scheffzek, K. | | Deposit date: | 2023-10-18 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.255 Å) | | Cite: | Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes.
Int J Mol Sci, 25, 2024
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8QVY
 | | Human NDPK-C unliganded | | Descriptor: | Nucleoside diphosphate kinase 3, PHOSPHATE ION | | Authors: | Werten, S, Amjadi, R, Scheffzek, K. | | Deposit date: | 2023-10-18 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes.
Int J Mol Sci, 25, 2024
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1X8Z
 | | Crystal structure of a pectin methylesterase inhibitor from Arabidopsis thaliana | | Descriptor: | invertase/pectin methylesterase inhibitor family protein | | Authors: | Hothorn, M, Wolf, S, Aloy, P, Greiner, S, Scheffzek, K. | | Deposit date: | 2004-08-19 | | Release date: | 2004-12-28 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structural insights into the target specificity of plant invertase and pectin methylesterase inhibitory proteins
Plant Cell, 16, 2004
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1ZR3
 | | Crystal structure of the macro-domain of human core histone variant macroH2A1.1 (form B) | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, histone macroH2A1.1 | | Authors: | Kustatscher, G, Hothorn, M, Pugieux, C, Scheffzek, K, Ladurner, A.G. | | Deposit date: | 2005-05-19 | | Release date: | 2006-02-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Splicing regulates NAD metabolite binding to histone macroH2A.
Nat.Struct.Mol.Biol., 12, 2005
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1ZR5
 | | Crystal structure of the macro-domain of human core histone variant macroH2A1.2 | | Descriptor: | H2AFY protein | | Authors: | Kustatscher, G, Hothorn, M, Pugieux, C, Scheffzek, K, Ladurner, A.G. | | Deposit date: | 2005-05-19 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Splicing regulates NAD metabolite binding to histone macroH2A.
Nat.Struct.Mol.Biol., 12, 2005
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1OPK
 | | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | | Descriptor: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | | Deposit date: | 2003-03-06 | | Release date: | 2003-04-08 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
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1OPJ
 | | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, MYRISTIC ACID, ... | | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | | Deposit date: | 2003-03-06 | | Release date: | 2003-04-08 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
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1X90
 | | Crystal structure of mutant form B of a pectin methylesterase inhibitor from Arabidopsis | | Descriptor: | invertase/pectin methylesterase inhibitor family protein | | Authors: | Hothorn, M, Wolf, S, Aloy, P, Greiner, S, Scheffzek, K. | | Deposit date: | 2004-08-19 | | Release date: | 2004-12-28 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Structural insights into the target specificity of plant invertase and pectin methylesterase inhibitory proteins
Plant Cell, 16, 2004
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1OPL
 | | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | | Descriptor: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, MYRISTIC ACID, proto-oncogene tyrosine-protein kinase | | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | | Deposit date: | 2003-03-06 | | Release date: | 2003-04-08 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.42 Å) | | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
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1X91
 | | Crystal structure of mutant form A of a pectin methylesterase inhibitor from Arabidopsis | | Descriptor: | invertase/pectin methylesterase inhibitor family protein | | Authors: | Hothorn, M, Wolf, S, Aloy, P, Greiner, S, Scheffzek, K. | | Deposit date: | 2004-08-19 | | Release date: | 2004-12-28 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural insights into the target specificity of plant invertase and pectin methylesterase inhibitory proteins
Plant Cell, 16, 2004
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1JAH
 | | H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MAGNESIUM | | Descriptor: | C-HA-RAS, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Schweins, T, Scheffzek, K, Assheuer, R, Wittinghofer, A. | | Deposit date: | 1996-12-15 | | Release date: | 1997-07-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+.
J.Mol.Biol., 266, 1997
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1JAI
 | | H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MANGANESE | | Descriptor: | C-HA-RAS, MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Schweins, T, Scheffzek, K, Assheuer, R, Wittinghofer, A. | | Deposit date: | 1996-12-15 | | Release date: | 1997-07-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+.
J.Mol.Biol., 266, 1997
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