6PFM
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![BU of 6pfm by Molmil](/molmil-images/mine/6pfm) | Crystal structure of GDC-0927 bound to estrogen receptor alpha | Descriptor: | (2S)-2-(4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-1-benzopyran-6-ol, Estrogen receptor | Authors: | Kiefer, J.R, Vinogradova, M, Liang, J, Zhang, B, Wang, X, Zbieg, J.R, Labadie, S.S, Li, J, Ray, N.C, Ortwine, D. | Deposit date: | 2019-06-21 | Release date: | 2019-07-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927. Bioorg.Med.Chem.Lett., 29, 2019
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1B3H
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1B2H
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1B1H
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![BU of 1b1h by Molmil](/molmil-images/mine/1b1h) | OLIGO-PEPTIDE BINDING PROTEIN/TRIPEPTIDE (LYS HPE LYS) COMPLEX | Descriptor: | PROTEIN (LYS HPE LYS), PROTEIN (OLIGO-PEPTIDE BINDING PROTEIN), URANYL (VI) ION | Authors: | Davies, T.G, Tame, J.R.H. | Deposit date: | 1998-11-10 | Release date: | 1998-11-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Relating structure to thermodynamics: the crystal structures and binding affinity of eight OppA-peptide complexes. Protein Sci., 8, 1999
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1B5H
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1B4H
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1B7H
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1B6H
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5IPF
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![BU of 5ipf by Molmil](/molmil-images/mine/5ipf) | Crystal structure of Hypoxanthine-guanine phosphoribosyltransferase from Schistosoma mansoni in complex with IMP | Descriptor: | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), INOSINIC ACID | Authors: | Romanello, L, Torini, J.R.S, Bird, L.E, Nettleship, J.E, Owens, R.J, DeMarco, R, Pereira, H.M, Brandao-Neto, J. | Deposit date: | 2016-03-09 | Release date: | 2017-03-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | In vitro and in vivo characterization of the multiple isoforms of Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferases. Mol. Biochem. Parasitol., 229, 2019
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6T64
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![BU of 6t64 by Molmil](/molmil-images/mine/6t64) | A model of the EIAV CA-SP hexamer (C6) from Gag-deltaMA spheres assembled at pH6 | Descriptor: | Gag polyprotein | Authors: | Dick, R.A, Xu, C, Morado, D.R, Kravchuk, V, Ricana, C.L, Lyddon, T.D, Broad, A.M, Feathers, J.R, Johnson, M.C, Vogt, V.M, Perilla, J.R, Briggs, J.A.G, Schur, F.K.M. | Deposit date: | 2019-10-17 | Release date: | 2020-01-15 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Plos Pathog., 16, 2020
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5JYG
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6T63
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![BU of 6t63 by Molmil](/molmil-images/mine/6t63) | A model of the EIAV CA-SP hexamer (C2) from Gag-deltaMA tubes assembled at pH6 | Descriptor: | Gag polyprotein | Authors: | Dick, R.A, Xu, C, Morado, D.R, Kravchuk, V, Ricana, C.L, Lyddon, T.D, Broad, A.M, Feathers, J.R, Johnson, M.C, Vogt, V.M, Perilla, J.R, Briggs, J.A.G, Schur, F.K.M. | Deposit date: | 2019-10-17 | Release date: | 2020-01-15 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Plos Pathog., 16, 2020
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3J1V
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5KK8
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![BU of 5kk8 by Molmil](/molmil-images/mine/5kk8) | Crystal structure of Nucleoside Diphosphate Kinase from Schistosoma mansoni in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase | Authors: | Torini, J.R.S, Romanello, L, Bird, L.E, Nettleship, J.E, Owens, R.J, Aller, P, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | Deposit date: | 2016-06-21 | Release date: | 2017-06-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs. Mol.Biochem.Parasitol., 2019
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6T61
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![BU of 6t61 by Molmil](/molmil-images/mine/6t61) | A model of the EIAV CA-SP hexamer (C2) from Gag-deltaMA tubes assembled at pH8 | Descriptor: | Gag polyprotein | Authors: | Dick, R.A, Xu, C, Morado, D.R, Kravchuk, V, Ricana, C.L, Lyddon, T.D, Broad, A.M, Feathers, J.R, Johnson, M.C, Vogt, V.M, Perilla, J.R, Briggs, J.A.G, Schur, F.K.M. | Deposit date: | 2019-10-17 | Release date: | 2020-01-15 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Plos Pathog., 16, 2020
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3J1X
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![BU of 3j1x by Molmil](/molmil-images/mine/3j1x) | A refined model of the prototypical Salmonella typhimurium T3SS basal body reveals the molecular basis for its assembly | Descriptor: | Protein PrgH | Authors: | Sgourakis, N.G, Bergeron, J.R.C, Worrall, L.J, Strynadka, N.C.J, Baker, D. | Deposit date: | 2012-07-10 | Release date: | 2013-05-22 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (11.7 Å) | Cite: | A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly. Plos Pathog., 9, 2013
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3J6D
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![BU of 3j6d by Molmil](/molmil-images/mine/3j6d) | Model of the PrgH-PrgK periplasmic rings | Descriptor: | Pathogenicity 1 island effector protein, Protein PrgH | Authors: | Bergeron, J.R.C, Strynadka, N.C.J. | Deposit date: | 2014-02-14 | Release date: | 2015-01-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (11.7 Å) | Cite: | The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body. Structure, 23, 2015
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5IOL
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![BU of 5iol by Molmil](/molmil-images/mine/5iol) | Crystal structure of Nucleoside Diphosphate Kinase from Schistosoma mansoni | Descriptor: | Nucleoside diphosphate kinase | Authors: | Torini, J.R.S, Romanello, L, Bird, L.E, Nettleship, J.E, Owens, R.J, Aller, P, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | Deposit date: | 2016-03-08 | Release date: | 2017-03-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.741 Å) | Cite: | Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs. Mol.Biochem.Parasitol., 2019
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3I4R
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![BU of 3i4r by Molmil](/molmil-images/mine/3i4r) | Nup107(aa658-925)/Nup133(aa517-1156) complex, H.sapiens | Descriptor: | Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133 | Authors: | Whittle, J.R.R, Schwartz, T.U. | Deposit date: | 2009-07-02 | Release date: | 2009-08-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.53 Å) | Cite: | Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element. J.Biol.Chem., 284, 2009
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3I5Q
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![BU of 3i5q by Molmil](/molmil-images/mine/3i5q) | Nup170(aa1253-1502) at 2.2 A, S.cerevisiae | Descriptor: | Nucleoporin NUP170 | Authors: | Whittle, J.R.R, Schwartz, T.U. | Deposit date: | 2009-07-06 | Release date: | 2009-08-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element. J.Biol.Chem., 284, 2009
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3I5P
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![BU of 3i5p by Molmil](/molmil-images/mine/3i5p) | Nup170(aa979-1502), S.cerevisiae | Descriptor: | Nucleoporin NUP170 | Authors: | Whittle, J.R.R, Schwartz, T.U. | Deposit date: | 2009-07-06 | Release date: | 2009-08-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element. J.Biol.Chem., 284, 2009
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1WUB
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![BU of 1wub by Molmil](/molmil-images/mine/1wub) | Crystal structure of the polyisoprenoid-binding protein, TT1927b, from Thermus thermophilus HB8 | Descriptor: | (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE, conserved hypothetical protein TT1927b | Authors: | Handa, N, Idaka, M, Terada, T, Hamana, H, Ishizuka, Y, Park, S.-Y, Tame, J.R.H, Doi-Katayama, Y, Hirota, H, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-12-03 | Release date: | 2004-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of a novel polyisoprenoid-binding protein from Thermus thermophilus HB8 Protein Sci., 14, 2005
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299D
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![BU of 299d by Molmil](/molmil-images/mine/299d) | CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: THE HAMMERHEAD RIBOZYME | Descriptor: | RNA HAMMERHEAD RIBOZYME | Authors: | Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A. | Deposit date: | 1996-12-14 | Release date: | 1997-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science, 274, 1996
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6PET
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![BU of 6pet by Molmil](/molmil-images/mine/6pet) | Crystal structure of 8-hydroxychromene compound 30 bound to estrogen receptor alpha | Descriptor: | (2S)-2-(4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-1-benzopyran-8-ol, (2S)-3-(3-hydroxyphenyl)-2-(4-iodophenyl)-4-methyl-2H-1-benzopyran-6-ol, CHLORIDE ION, ... | Authors: | Kiefer, J.R, Vinogradova, M, Liang, J, Wang, X, Zbieg, J, Labadie, S.S, Zhang, B, Li, J, Liang, W. | Deposit date: | 2019-06-20 | Release date: | 2019-07-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.203 Å) | Cite: | Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927. Bioorg.Med.Chem.Lett., 29, 2019
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6MOS
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