1UE1
 
 | | Crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosis | | Descriptor: | Single-strand binding protein, ZINC ION | | Authors: | Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Sekar, K, Varshney, U, Vijayan, M, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-05-08 | | Release date: | 2004-02-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of Mycobacterium tuberculosis single-stranded DNA-binding protein. Variability in quaternary structure and its implications
J.MOL.BIOL., 331, 2003
|
|
1UE7
 | | Crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosis | | Descriptor: | Single-strand binding protein | | Authors: | Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Sekar, K, Varshney, U, Vijayan, M, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-05-09 | | Release date: | 2004-02-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of Mycobacterium tuberculosis single-stranded DNA-binding protein. Variability in quaternary structure and its implications
J.MOL.BIOL., 331, 2003
|
|
2IEL
 | | CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus | | Descriptor: | Hypothetical Protein TT0030 | | Authors: | Zhu, J, Huang, J, Stepanyuk, G, Chen, L, Chang, J, Zhao, M, Xu, H, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2006-09-19 | | Release date: | 2006-11-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus AT 1.6 ANGSTROMS RESOLUTION
To be Published
|
|
4N19
 | | Structural basis of conformational transitions in the active site and 80 s loop in the FK506 binding protein FKBP12 | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1A, SULFATE ION | | Authors: | Mustafi, S.M, Brecher, M.B, Zhang, J, Li, H.M, Lemaster, D.M, Hernandez, G. | | Deposit date: | 2013-10-03 | | Release date: | 2014-02-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structural basis of conformational transitions in the active site and 80's loop in the FK506-binding protein FKBP12.
Biochem.J., 458, 2014
|
|
7F6M
 | | Crystal structure of APC complexed with a peptide inhibitor MAI-516 | | Descriptor: | Adenomatous polyposis coli protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Song, K, Zhang, J. | | Deposit date: | 2021-06-25 | | Release date: | 2022-06-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Discovery of Efficient Adenomatous Polyposis Coli - Rho Guanine Nucleotide Exchange Factor 4 Inhibitors by Employing High Binding Affinity Tracer
To Be Published
|
|
7F7O
 | | APC-Asef FP assay tracer | | Descriptor: | Adenomatous polyposis coli protein, N-[3',6'-bis(oxidanyl)-3-oxidanylidene-spiro[2-benzofuran-1,9'-xanthene]-5-yl]methanethioamide, Tracer 7 | | Authors: | Yang, X, Zhang, J. | | Deposit date: | 2021-06-30 | | Release date: | 2022-07-06 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The tracer of FP assay for screening APC-Asef inhbitors
To Be Published
|
|
2IDG
 | | Crystal Structure of hypothetical protein AF0160 from Archaeoglobus fulgidus | | Descriptor: | Hypothetical protein AF0160 | | Authors: | Zhao, M, Zhang, M, Chang, J, Chen, L, Xu, H, Li, Y, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2006-09-15 | | Release date: | 2006-11-14 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Crystal structure of Hypothetical Protein AF0160 from Archaeoglobus fulgidus at 2.69 Angstrom resolution
To be Published
|
|
7FBY
 | | Crystal Structure of PH0140 from Pyrococcus horikosii OT3 | | Descriptor: | 1,2-ETHANEDIOL, ISOLEUCINE, Transcriptional regulatory protein | | Authors: | Richard, M, Ahmad, M, Pal, R.K, Biswal, B.K, Jeyakanthan, J. | | Deposit date: | 2021-07-13 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Crystal Structure of PH0140 from Pyrococcus horikosii OT3
To Be Published
|
|
2ID0
 | | Escherichia coli RNase II | | Descriptor: | Exoribonuclease 2, MANGANESE (II) ION | | Authors: | Zuo, Y, Zhang, J, Wang, Y, Malhotra, A. | | Deposit date: | 2006-09-13 | | Release date: | 2006-10-03 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural Basis for Processivity and Single-Strand Specificity of RNase II.
Mol.Cell, 24, 2006
|
|
2J2F
 | | The T199D Mutant of Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean) | | Descriptor: | ACYL-[ACYL-CARRIER-PROTEIN] DESATURASE, FE (III) ION | | Authors: | Guy, J.E, Abreu, I.A, Moche, M, Lindqvist, Y, Whittle, E, Shanklin, J. | | Deposit date: | 2006-08-16 | | Release date: | 2006-10-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | A Single Mutation in the Castor {Delta}9-18:0- Desaturase Changes Reaction Partitioning from Desaturation to Oxidase Chemistry.
Proc.Natl.Acad.Sci.USA, 103, 2006
|
|
7TQA
 | | Crystal Structure of monoclonal S9.6 Fab | | Descriptor: | Fab S9.6 heavy chain, Fab S9.6 light chain, GLYCEROL, ... | | Authors: | Bou-Nader, C, Zhang, J. | | Deposit date: | 2022-01-26 | | Release date: | 2022-03-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.328 Å) | | Cite: | Structural basis of R-loop recognition by the S9.6 monoclonal antibody.
Nat Commun, 13, 2022
|
|
7TQB
 | |
8WZQ
 | | Crystal structure of SARS-Cov-2 main protease V186F mutant in complex with CCF0058981 | | Descriptor: | 2-(benzotriazol-1-yl)-~{N}-[(3-chlorophenyl)methyl]-~{N}-[4-(1~{H}-imidazol-5-yl)phenyl]ethanamide, 3C-like proteinase nsp5 | | Authors: | Zou, X.F, Jiang, H.H, Zhou, X.L, Zhang, J, Li, J. | | Deposit date: | 2023-11-02 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Crystal structure of SARS-CoV-2 main protease (M pro ) mutants in complex with the non-covalent inhibitor CCF0058981.
Biochem.Biophys.Res.Commun., 692, 2024
|
|
8WZP
 | | Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with CCF0058981 | | Descriptor: | 2-(benzotriazol-1-yl)-~{N}-[(3-chlorophenyl)methyl]-~{N}-[4-(1~{H}-imidazol-5-yl)phenyl]ethanamide, 3C-like proteinase nsp5 | | Authors: | Jiang, H.H, Zou, X.F, Zhou, X.L, Zhang, J, Li, J. | | Deposit date: | 2023-11-02 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Crystal structure of SARS-CoV-2 main protease (M pro ) mutants in complex with the non-covalent inhibitor CCF0058981.
Biochem.Biophys.Res.Commun., 692, 2024
|
|
8J37
 | | Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with PF00835231 | | Descriptor: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | | Authors: | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | | Deposit date: | 2023-04-16 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Crystal structure of SARS-Cov-2 main protease
K90R mutant in complex with PF00835231
To Be Published
|
|
8J35
 | | Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with PF00835231 | | Descriptor: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | | Authors: | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | | Deposit date: | 2023-04-16 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Crystal structure of SARS-Cov-2 main protease
G15S mutant in complex with PF00835231
To Be Published
|
|
8J3A
 | | Crystal structure of SARS-Cov-2 main protease Y54C mutant in complex with PF00835231 | | Descriptor: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | | Authors: | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | | Deposit date: | 2023-04-16 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Crystal structure of SARS-Cov-2 main protease
Y54C mutant in complex with PF00835231
To Be Published
|
|
5EJO
 | | Crystal structure of the winged helix domain in Chromatin assembly factor 1 subunit p90 | | Descriptor: | Chromatin assembly factor 1 subunit p90 | | Authors: | Zhang, K, Gao, Y, Li, J, Burgess, R, Han, J, Liang, H, Zhang, Z, Liu, Y. | | Deposit date: | 2015-11-02 | | Release date: | 2016-03-16 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks
Nucleic Acids Res., 44, 2016
|
|
8H4Q
 | |
8H4H
 | |
8J2P
 | | Crystal structure of PML B-box2 | | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Zhou, C, Zang, N, Zhang, J. | | Deposit date: | 2023-04-15 | | Release date: | 2023-09-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Cancer Discov, 13, 2023
|
|
8J25
 | | Crystal structure of PML B-box2 mutant | | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Zhou, C, Zang, N, Zhang, J. | | Deposit date: | 2023-04-14 | | Release date: | 2023-09-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Cancer Discov, 13, 2023
|
|
6JF1
 | | Crystal structure of the substrate binding protein of a methionine transporter from Streptococcus pneumoniae | | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Jha, B, Vyas, R, Bhushan, J, Sehgal, D, Biswal, B.K. | | Deposit date: | 2019-02-07 | | Release date: | 2019-07-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural insights into the substrate specificity of SP_0149, the substrate-binding protein of a methionine ABC transporter from Streptococcus pneumoniae.
Acta Crystallogr.,Sect.F, 75, 2019
|
|
7MU8
 | | Structure of the minimally glycosylated human CEACAM1 N-terminal domain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, ... | | Authors: | Belcher Dufrisne, M, Swope, N, Kieber, M, Yang, J.Y, Han, J, Li, J, Moremen, K.W, Prestegard, J.H, Columbus, L. | | Deposit date: | 2021-05-14 | | Release date: | 2022-02-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Human CEACAM1 N-domain dimerization is independent from glycan modifications.
Structure, 30, 2022
|
|
8U44
 | | CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06 | | Descriptor: | 05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Moore, N, Han, J, Ward, A.B, Wilson, I.A. | | Deposit date: | 2023-09-08 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Persistence of germinal center B cell responses after influenza virus vaccination in humans
To Be Published
|
|
