6WB1

+3 extended HIV-1 reverse transcriptase initiation complex core (intermediate state)

Summary for 6WB1

Entry DOI	10.2210/pdb6wb1/pdb
EMDB information	21584
Descriptor	HIV-1 viral RNA genome fragment, tRNA lysine 3, REVERSE TRANSCRIPTASE/RIBONUCLEASE H, ... (4 entities in total)
Functional Keywords	reverse transcriptase, rna, protein-rna complex, trna, polymerase, viral protein, viral protein-rna complex, viral protein/rna
Biological source	Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) More
Total number of polymer chains	4
Total formula weight	174268.15
Authors	Larsen, K.P.,Jackson, L.N.,Kappel, K.,Zhang, J.,Chen, D.H.,Puglisi, E.V. (deposition date: 2020-03-26, release date: 2020-06-24, Last modification date: 2024-03-06)
Primary citation	Larsen, K.P.,Choi, J.,Jackson, L.N.,Kappel, K.,Zhang, J.,Ha, B.,Chen, D.H.,Puglisi, E.V. Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription. J.Mol.Biol., 432:4499-4522, 2020 Cited by PubMed: 32512005 DOI: 10.1016/j.jmb.2020.06.003 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.7 Å)

Structure validation