2G94
 
 | | Crystal structure of beta-secretase bound to a potent and highly selective inhibitor. | | Descriptor: | Beta-secretase 1, N~2~-[(2R,4S,5S)-5-{[N-{[(3,5-DIMETHYL-1H-PYRAZOL-1-YL)METHOXY]CARBONYL}-3-(METHYLSULFONYL)-L-ALANYL]AMINO}-4-HYDROXY-2,7-DIMETHYLOCTANOYL]-N-ISOBUTYL-L-VALINAMIDE | | Authors: | Hong, L, Ghosh, A, Tang, J. | | Deposit date: | 2006-03-05 | | Release date: | 2006-04-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors.
J.Am.Chem.Soc., 128, 2006
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1FB7
 | | CRYSTAL STRUCTURE OF AN IN VIVO HIV-1 PROTEASE MUTANT IN COMPLEX WITH SAQUINAVIR: INSIGHTS INTO THE MECHANISMS OF DRUG RESISTANCE | | Descriptor: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, HIV-1 PROTEASE | | Authors: | Hong, L, Zhang, X.C, Hartsuck, J.A, Tang, J. | | Deposit date: | 2000-07-14 | | Release date: | 2000-12-13 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: insights into the mechanisms of drug resistance.
Protein Sci., 9, 2000
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1FKN
 | | Structure of Beta-Secretase Complexed with Inhibitor | | Descriptor: | MEMAPSIN 2, inhibitor | | Authors: | Hong, L, Koelsch, G, Lin, X, Wu, S, Terzyan, S, Ghosh, A, Zhang, X.C, Tang, J. | | Deposit date: | 2000-08-09 | | Release date: | 2000-10-09 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor.
Science, 290, 2000
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4NC1
 | | Crystal Structure of TcdA-A2 Bound to A20.1 VHH and A26.8 VHH | | Descriptor: | A20.1 VHH, A26.8 VHH, Cell wall-binding repeat protein | | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | | Deposit date: | 2013-10-23 | | Release date: | 2013-12-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile.
J.Biol.Chem., 289, 2014
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4NBY
 | | Crystal Structure of TcdA-A2 Bound to Two Molecules of A20.1 VHH | | Descriptor: | A20.1 VHH, Cell wall-binding repeat protein | | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E, Klassen, J.S, Ng, K.K.S. | | Deposit date: | 2013-10-23 | | Release date: | 2013-12-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile.
J.Biol.Chem., 289, 2014
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4NC0
 | | Crystal Structure of TcdA-A2 Bound to A26.8 VHH | | Descriptor: | A26.8 VHH, Cell wall-binding repeat protein | | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | | Deposit date: | 2013-10-23 | | Release date: | 2013-12-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile.
J.Biol.Chem., 289, 2014
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4NBX
 | | Crystal Structure of Clostridium difficile Toxin A fragment TcdA-A1 Bound to A20.1 VHH | | Descriptor: | A20.1 VHH, TcdA | | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | | Deposit date: | 2013-10-23 | | Release date: | 2013-12-11 | | Last modified: | 2014-02-12 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile.
J.Biol.Chem., 289, 2014
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4NBZ
 | | Crystal Structure of TcdA-A1 Bound to A26.8 VHH | | Descriptor: | A26.8 VHH, TcdA | | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | | Deposit date: | 2013-10-23 | | Release date: | 2013-12-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile.
J.Biol.Chem., 289, 2014
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7AOY
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4NC2
 | | Crystal structure of TcdB-B1 bound to B39 VHH | | Descriptor: | B39 VHH, Toxin B | | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | | Deposit date: | 2013-10-23 | | Release date: | 2013-12-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile.
J.Biol.Chem., 289, 2014
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4Q58
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4Q59
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5J7I
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2BX4
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2BX3
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7K75
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7K76
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7CG7
 | | Cryo-EM structure of the flagellar MS ring with C34 symmetry from Salmonella | | Descriptor: | Flagellar M-ring protein | | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | Deposit date: | 2020-06-30 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
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7CGO
 | | Cryo-EM structure of the flagellar motor-hook complex from Salmonella | | Descriptor: | Flagellar L-ring protein, Flagellar M-ring protein, Flagellar MS ring L1, ... | | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | Deposit date: | 2020-07-01 | | Release date: | 2021-04-28 | | Last modified: | 2021-05-26 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
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7CG4
 | | Cryo-EM structure of the flagellar export apparatus with FliE from Salmonella | | Descriptor: | Flagellar biosynthetic protein FliP, Flagellar hook-basal body complex protein FliE | | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | Deposit date: | 2020-06-30 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
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7CBL
 | | Cryo-EM structure of the flagellar LP ring from Salmonella | | Descriptor: | Flagellar L-ring protein, Flagellar P-ring protein, OCTANOIC ACID (CAPRYLIC ACID) | | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | Deposit date: | 2020-06-12 | | Release date: | 2021-04-28 | | Last modified: | 2021-05-26 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
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7CBM
 | | Cryo-EM structure of the flagellar distal rod with partial hook from Salmonella | | Descriptor: | Flagellar basal-body rod protein FlgF, Flagellar basal-body rod protein FlgG, Flagellar hook protein FlgE | | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | Deposit date: | 2020-06-12 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
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7CGB
 | | Cryo-EM structure of the flagellar hook from Salmonella | | Descriptor: | Flagellar hook protein FlgE | | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | Deposit date: | 2020-07-01 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
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7CG0
 | | Cryo-EM structure of the flagellar proximal rod with FliF peptides from Salmonella | | Descriptor: | Flagellar MS ring L1, Flagellar MS ring L2, Flagellar basal body rod protein FlgB, ... | | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | Deposit date: | 2020-06-30 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
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7E80
 | | Cryo-EM structure of the flagellar rod with hook and export apparatus from Salmonella | | Descriptor: | Flagellar MS ring L1, Flagellar MS ring L2, Flagellar basal body rod protein FlgB, ... | | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | | Deposit date: | 2021-02-28 | | Release date: | 2021-04-28 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
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