4BG1

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 1-(3-Carboxypropyl)-1-methylpyrrolidin-1-ium chloride

Summary for 4BG1

Entry DOI	10.2210/pdb4bg1/pdb
Related	4BGK 4BGM 4BHF 4BHI 4C5W
Descriptor	GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 1-(3-carboxypropyl)-1-methylpyrrolidin-1-ium, ... (6 entities in total)
Functional Keywords	oxidoreductase, gamma-butyrobetaine hydroxylase, gamma-bbh, gamma-butyrobetaine, 2-oxoglutarate dioxygenase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	45472.04
Authors	Tars, K.,Leitans, J.,Kazaks, A. (deposition date: 2013-03-22, release date: 2014-03-12, Last modification date: 2023-12-20)
Primary citation	Tars, K.,Leitans, J.,Kazaks, A.,Zelencova, D.,Liepinsh, E.,Kuka, J.,Makrecka, M.,Lola, D.,Andrianovs, V.,Gustina, D.,Grinberga, S.,Liepinsh, E.,Kalvinsh, I.,Dambrova, M.,Loza, E.,Pugovics, O. Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. J.Med.Chem., 57:2213-, 2014 Cited by PubMed: 24571165 DOI: 10.1021/JM401603E PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation