1B6Y
 
 | | 3,N4-ETHENO-2'-DEOXYCYTIDINE OPPOSITE ADENINE IN AN 11-MER DUPLEX, SOLUTION STRUCTURE FROM NMR AND MOLECULAR DYNAMICS, 2 STRUCTURES | | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*(EDC)P*CP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*GP*AP*GP*TP*AP*CP*G)-3' | | Authors: | Korobka, A, Cullinan, D, Cosman, M, Grollman, A.P, Patel, D.J, Eisenberg, M, De Los Santos, C. | | Deposit date: | 1999-01-19 | | Release date: | 1999-01-27 | | Last modified: | 2024-04-10 | | Method: | SOLUTION NMR | | Cite: | Solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite 2'-deoxyadenosine, determined by NMR spectroscopy and restrained molecular dynamics.
Biochemistry, 35, 1996
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1AX7
 | | SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT POSITIONED AT A TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES | | Descriptor: | 2-AMINOFLUORENE, DNA DUPLEX D(AAC-[AF]G-CTACCATCC)D(GGATGGTAG) | | Authors: | Mao, B, Gu, Z, Gorin, A.A, Hingerty, B.E, Broyde, S, Patel, D.J. | | Deposit date: | 1997-10-30 | | Release date: | 1998-07-01 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the aminofluorene-stacked conformer of the syn [AF]-C8-dG adduct positioned at a template-primer junction.
Biochemistry, 36, 1997
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4HRE
 | | Crystal Structure of p11/Annexin A2 Heterotetramer in Complex with SMARCA3 Peptide | | Descriptor: | Annexin A2, Helicase-like transcription factor, Protein S100-A10 | | Authors: | Gao, P, Patel, D.J. | | Deposit date: | 2012-10-27 | | Release date: | 2013-03-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.7852 Å) | | Cite: | SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
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4HRH
 | | Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide | | Descriptor: | Helicase-like transcription factor, Protein S100-A10, Annexin A2, ... | | Authors: | Gao, P, Patel, D.J. | | Deposit date: | 2012-10-27 | | Release date: | 2013-03-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.001 Å) | | Cite: | SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
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4JVH
 | | Structure of the star domain of quaking protein in complex with RNA | | Descriptor: | Protein quaking, RNA (5'-R(*UP*UP*CP*AP*CP*UP*AP*AP*CP*AP*A)-3'), SULFATE ION | | Authors: | Teplova, M, Hafner, M, Teplov, D, Essig, K, Tuschl, T, Patel, D.J. | | Deposit date: | 2013-03-25 | | Release date: | 2013-05-08 | | Method: | X-RAY DIFFRACTION (3.501 Å) | | Cite: | Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
Genes Dev., 27, 2013
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1BIV
 | | BOVINE IMMUNODEFICIENCY VIRUS TAT-TAR COMPLEX, NMR, 5 STRUCTURES | | Descriptor: | TAR RNA, TAT PEPTIDE | | Authors: | Ye, X, Kumar, R.A, Patel, D.J. | | Deposit date: | 1996-06-12 | | Release date: | 1996-12-23 | | Last modified: | 2024-04-10 | | Method: | SOLUTION NMR | | Cite: | Molecular recognition in the bovine immunodeficiency virus Tat peptide-TAR RNA complex.
Chem.Biol., 2, 1995
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4JVY
 | | Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA | | Descriptor: | Female germline-specific tumor suppressor gld-1, RNA (5'-R(P*CP*UP*AP*AP*CP*AP*A)-3') | | Authors: | Teplova, M, Hafner, M, Teplov, D, Essig, K, Tuschl, T, Patel, D.J. | | Deposit date: | 2013-03-26 | | Release date: | 2013-05-08 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.853 Å) | | Cite: | Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
Genes Dev., 27, 2013
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4K8V
 | | Structure of cyclic GMP-AMP Synthase (cGAS) | | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | | Authors: | Gao, P, Wu, Y, Patel, D.J. | | Deposit date: | 2013-04-18 | | Release date: | 2013-05-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Cell(Cambridge,Mass.), 153, 2013
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4K80
 | | Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 2:0 ceramide-1-phosphate (2:0-C1P) | | Descriptor: | (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | | Deposit date: | 2013-04-17 | | Release date: | 2013-07-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.051 Å) | | Cite: | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
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5U34
 | | Crystal structure of AacC2c1-sgRNA binary complex | | Descriptor: | CRISPR-associated endonuclease C2c1, sgRNA | | Authors: | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | | Deposit date: | 2016-12-01 | | Release date: | 2017-01-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.255 Å) | | Cite: | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
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5U30
 | | Crystal structure of AacC2c1-sgRNA-extended target DNA ternary complex | | Descriptor: | CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ... | | Authors: | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | | Deposit date: | 2016-12-01 | | Release date: | 2017-01-25 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
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4E8U
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4DOV
 | | Structure of free mouse ORC1 BAH domain | | Descriptor: | Origin recognition complex subunit 1 | | Authors: | Song, J, Patel, D.J. | | Deposit date: | 2012-02-10 | | Release date: | 2012-03-07 | | Last modified: | 2012-04-11 | | Method: | X-RAY DIFFRACTION (1.696 Å) | | Cite: | The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
Nature, 484, 2012
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5U33
 | | Crystal structure of AacC2c1-sgRNA-extended non-target DNA ternary complex | | Descriptor: | CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ... | | Authors: | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | | Deposit date: | 2016-12-01 | | Release date: | 2017-01-25 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.75 Å) | | Cite: | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
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4EN5
 | | Crystal structure of fluoride riboswitch, Tl-Acetate soaked | | Descriptor: | FLUORIDE ION, Fluoride riboswitch, MAGNESIUM ION, ... | | Authors: | Ren, A.M, Rajashankar, K.R, Patel, D.J. | | Deposit date: | 2012-04-12 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.957 Å) | | Cite: | Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
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4ENA
 | | Crystal structure of fluoride riboswitch, soaked in Cs+ | | Descriptor: | CESIUM ION, FLUORIDE ION, Fluoride riboswitch, ... | | Authors: | Ren, A.M, Rajashankar, K.R, Patel, D.J. | | Deposit date: | 2012-04-12 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
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4DA4
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4DOW
 | | Structure of mouse ORC1 BAH domain bound to H4K20me2 | | Descriptor: | Histone H4, Origin recognition complex subunit 1 | | Authors: | Song, J, Patel, D.J. | | Deposit date: | 2012-02-10 | | Release date: | 2012-03-07 | | Last modified: | 2012-04-11 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
Nature, 484, 2012
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4ENC
 | | Crystal structure of fluoride riboswitch | | Descriptor: | FLUORIDE ION, Fluoride riboswitch, MAGNESIUM ION, ... | | Authors: | Ren, A.M, Rajashankar, K.R, Patel, D.J. | | Deposit date: | 2012-04-12 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.272 Å) | | Cite: | Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
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4EZH
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5U31
 | | Crystal structure of AacC2c1-sgRNA-8mer substrate DNA ternary complex | | Descriptor: | CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ... | | Authors: | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | | Deposit date: | 2016-12-01 | | Release date: | 2017-01-25 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
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4EZ4
 | | free KDM6B structure | | Descriptor: | Lysine-specific demethylase 6B, N-OXALYLGLYCINE, NICKEL (II) ION, ... | | Authors: | Cheng, Z.J, Patel, D.J. | | Deposit date: | 2012-05-02 | | Release date: | 2012-08-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature, 488, 2012
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4ENB
 | | Crystal structure of fluoride riboswitch, bound to Iridium | | Descriptor: | FLUORIDE ION, Fluoride riboswitch, IRIDIUM HEXAMMINE ION, ... | | Authors: | Ren, A.M, Rajashankar, K.R, Patel, D.J. | | Deposit date: | 2012-04-12 | | Release date: | 2012-05-09 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
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4F1N
 | | Crystal structure of Kluyveromyces polysporus Argonaute with a guide RNA | | Descriptor: | KpAGO, RNA 5'-R(P*UP*AP*AP*AP*AP*AP*AP*AP*A)-3' | | Authors: | Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J. | | Deposit date: | 2012-05-07 | | Release date: | 2012-06-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.187 Å) | | Cite: | Structure of yeast Argonaute with guide RNA.
Nature, 486, 2012
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4EYU
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