7YGN
 
 | | Cryo-EM structure of the Mili in complex with piRNA | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-11 | | Release date: | 2024-01-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFX
 | | Cryo-EM structure of Hili in complex with piRNA | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-09 | | Release date: | 2024-01-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFQ
 | | Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex | | Descriptor: | MAGNESIUM ION, Piwi, RNA (5'-R(*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-08 | | Release date: | 2024-02-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7WKO
 | | ICP1 Csy1-2 complex | | Descriptor: | Csy1, Csy2 | | Authors: | Zhang, M, Peng, R. | | Deposit date: | 2022-01-10 | | Release date: | 2023-04-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7EA8
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7WKP
 | | ICP1 Csy4 | | Descriptor: | 3' stem loop crRNA, Csy4 | | Authors: | Zhang, M, Peng, R. | | Deposit date: | 2022-01-10 | | Release date: | 2023-04-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7E5R
 | | SARS-CoV-2 S trimer with three-antibody cocktail complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | | Deposit date: | 2021-02-20 | | Release date: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms.
Cell Res., 31, 2021
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7E5S
 | | SARS-CoV-2 S trimer with four-antibody cocktail complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | | Deposit date: | 2021-02-20 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms.
Cell Res., 31, 2021
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7XXB
 | | IAA bound state of AtPIN3 | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, Auxin efflux carrier component 3 | | Authors: | Su, N. | | Deposit date: | 2022-05-29 | | Release date: | 2022-08-10 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
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5ZF2
 | | Crystal structure of Trxlp from Edwardsiella tarda EIB202 | | Descriptor: | SULFATE ION, Thioredoxin (H-type,TRX-H) | | Authors: | Yang, C, Quan, S. | | Deposit date: | 2018-03-02 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection.
Plos Pathog., 15, 2019
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7E8O
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7E8J
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7E8K
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7DZE
 | | Fabp ground state captured by XFELs | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZH
 | | intermediate of FABP with a delay time of 100 ns | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZF
 | | Intermediate of FABP with a delay time of 10 ns | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZG
 | | Intermediate of FABP with a delay time of 30 ns | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZI
 | | intermediate of FABP with a delay time of 300 ns | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZJ
 | | Fabp protein before hv | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZK
 | | Fabp protein after hv | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZL
 | | A69C-M71L mutant of Fabp protein | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7VWZ
 | | Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Lin, W, Feng, Y, Shi, J. | | Deposit date: | 2021-11-12 | | Release date: | 2022-06-08 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
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7VWY
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7VEH
 | | Type I-F Anti-CRISPR protein AcrIF13 | | Descriptor: | AcrIF13 | | Authors: | Gao, T, Feng, Y. | | Deposit date: | 2021-09-08 | | Release date: | 2022-07-06 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Mechanistic insights into the inhibition of the CRISPR-Cas surveillance complex by anti-CRISPR protein AcrIF13.
J.Biol.Chem., 298, 2022
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7VLN
 | | NSD2-PWWP1 domain bound with an imidazol-5-yl benzonitrile compound | | Descriptor: | 4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile, Histone-lysine N-methyltransferase NSD2 | | Authors: | Cao, D.Y, Li, Y.L, Li, J, Xiong, B. | | Deposit date: | 2021-10-05 | | Release date: | 2022-07-06 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.
J.Med.Chem., 65, 2022
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