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2LK4
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BU of 2lk4 by Molmil
Structural and mechanistic insights into the interaction between PAT Pyk2 and Paxillin LD motif
Descriptor: Protein-tyrosine kinase 2-beta
Authors:Vanarotti, M, Miller, D, Guibao, C, Zheng, J.
Deposit date:2011-10-04
Release date:2012-10-10
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
6CKV
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BU of 6ckv by Molmil
Solution NMR structure of human BOK
Descriptor: Bcl-2-related ovarian killer protein
Authors:Grace, C.R, Zheng, J, Moldoveanu, T.
Deposit date:2018-03-01
Release date:2018-05-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis.
Cell Rep, 23, 2018
8GUG
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BU of 8gug by Molmil
Structure of VPA0770 toxin bound to VPA0769 antitoxin in Vibrio parahaemolyticus
Descriptor: DUF2384 domain-containing protein, RES domain-containing protein
Authors:Song, X.J, Zhang, Y, Xu, Y.Y, Lin, Z.
Deposit date:2022-09-12
Release date:2023-07-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural insights of the toxin-antitoxin system VPA0770-VPA0769 in Vibrio parahaemolyticus.
Int.J.Biol.Macromol., 242, 2023
8G75
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BU of 8g75 by Molmil
SARS-CoV-2 spike/Nb4 complex with 2 RBDs up and 3 Nb4 bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-4, ...
Authors:Ye, G, Bu, F, Liu, B, Li, F.
Deposit date:2023-02-16
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19.
J.Virol., 97, 2023
8G73
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BU of 8g73 by Molmil
SARS-CoV-2 spike/Nb3 complex with 2 RBDs up and 3 Nb3 bound at 2.5 A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-3, ...
Authors:Ye, G, Bu, F, Liu, B, Li, F.
Deposit date:2023-02-16
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19.
J.Virol., 97, 2023
8G72
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BU of 8g72 by Molmil
SARS-CoV-2 spike/Nb2 complex with 1 RBD up (local refinement at 5.6 A)
Descriptor: Nanosota-2, Spike glycoprotein
Authors:Ye, G, Bu, F, Liu, B, Li, F.
Deposit date:2023-02-16
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19.
J.Virol., 97, 2023
8G74
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BU of 8g74 by Molmil
SARS-CoV-2 spike/Nb3 complex with 1 RBD up and 2 Nb3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-3, ...
Authors:Ye, G, Bu, F, Liu, B, Li, F.
Deposit date:2023-02-16
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19.
J.Virol., 97, 2023
5VTM
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BU of 5vtm by Molmil
The crystal structure of minor pseudopilin ternary complex of XcpVWX from the Type 2 secretion system of Pseudomonas aeruginosa
Descriptor: CALCIUM ION, Type II secretion system protein I, Type II secretion system protein J, ...
Authors:Zhang, Y, Jia, Z.
Deposit date:2017-05-17
Release date:2018-05-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.041 Å)
Cite:Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa.
PLoS Pathog., 14, 2018
6BHJ
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BU of 6bhj by Molmil
Structure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamer
Descriptor: 38-MER RNA-DNA Aptamer, GLYCEROL, HIV-1 REVERSE TRANSCRIPTASE P51 subunit, ...
Authors:Ruiz, F.X, Miller, M.T, Tuske, S, Das, K, Arnold, E.
Deposit date:2017-10-30
Release date:2018-10-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Integrative Structural Biology Studies of HIV-1 Reverse Transcriptase Binding to a High-Affinity DNA Aptamer
Curr Res Struct Biol, 2020
6JIM
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BU of 6jim by Molmil
Viral helicase protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM ION, CHLORIDE ION, ...
Authors:Law, Y.S.
Deposit date:2019-02-22
Release date:2019-04-10
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase.
Proc.Natl.Acad.Sci.USA, 116, 2019
7CZA
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BU of 7cza by Molmil
Hexachlorobenzene monooxygenase (HcbA1) from Nocardioides sp. strain PD653 complexed with FMN
Descriptor: FLAVIN MONONUCLEOTIDE, Hexachlorobenzene oxidative dehalogenase
Authors:Guo, Y, Zheng, J.T, Zhou, N.Y.
Deposit date:2020-09-07
Release date:2020-09-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Hexachlorobenzene Monooxygenase Substrate Selectivity and Catalysis: Structural and Biochemical Insights.
Appl.Environ.Microbiol., 87, 2020
8IAB
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BU of 8iab by Molmil
The Arabidopsis CLCa transporter bound with chloride, ATP and PIP2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Chloride channel protein CLC-a, ...
Authors:Yang, Z, Zhang, X, Zhang, P.
Deposit date:2023-02-08
Release date:2023-08-02
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Molecular mechanism underlying regulation of Arabidopsis CLCa transporter by nucleotides and phospholipids.
Nat Commun, 14, 2023
8IAD
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BU of 8iad by Molmil
The Arabidopsis CLCa transporter bound with nitrate, ATP and PIP2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chloride channel protein CLC-a, MAGNESIUM ION, ...
Authors:Yang, Z, Zhang, X, Zhang, P.
Deposit date:2023-02-08
Release date:2023-08-02
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Molecular mechanism underlying regulation of Arabidopsis CLCa transporter by nucleotides and phospholipids.
Nat Commun, 14, 2023
4OVA
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BU of 4ova by Molmil
Structure of the two tandem Tudor domains and a new identified KH0 domain from human Fragile X Mental Retardation Protein
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fragile X mental retardation protein 1
Authors:Chen, Z.H, Chen, Z.Z.
Deposit date:2014-02-21
Release date:2015-02-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:The amino-terminal structure of human fragile X mental retardation protein obtained using precipitant-immobilized imprinted polymers
Nat Commun, 6, 2015
4RAZ
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BU of 4raz by Molmil
Crystal structure of Magnetospirillum gryphiswaldense MSR-1 holo-Fur
Descriptor: 1,2-ETHANEDIOL, DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION
Authors:Deng, Z, Wang, Q, Chen, Z.
Deposit date:2014-09-12
Release date:2015-07-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator.
Nat Commun, 6
4RAY
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BU of 4ray by Molmil
Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Apo-Fur
Descriptor: CITRATE ANION, DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), SULFATE ION
Authors:Deng, Z, Liu, Z, Chen, Z.
Deposit date:2014-09-12
Release date:2015-07-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator.
Nat Commun, 6
7DBW
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BU of 7dbw by Molmil
PnpA1, the oxygenase component of a two-component para-nitrophenol hydroxylase from Rhodococcus imtechensis RKJ300
Descriptor: 4-hydroxyphenylacetate 3-hydroxylase
Authors:Guo, Y, Zheng, J.T, Zhou, N.Y.
Deposit date:2020-10-22
Release date:2020-11-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Single-Component and Two-Component para -Nitrophenol Monooxygenases: Structural Basis for Their Catalytic Difference.
Appl.Environ.Microbiol., 87, 2021
4RB3
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BU of 4rb3 by Molmil
Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Fur-Mn2+-feoAB1 operator
Descriptor: DNA (25-MER), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION, ...
Authors:Deng, Z, Chen, Z.
Deposit date:2014-09-12
Release date:2015-07-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator.
Nat Commun, 6
4RB0
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BU of 4rb0 by Molmil
Crystal structure of Magnetospirillum gryphiswaldense MSR-1 SeMet-Apo-Fur
Descriptor: CITRATE ANION, DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), SULFATE ION
Authors:Deng, Z, Chen, Z.
Deposit date:2014-09-12
Release date:2015-07-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator.
Nat Commun, 6
4RB2
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BU of 4rb2 by Molmil
Crystal structure of Magnetospirillum gryphiswaldense MSR-1 SeMet-Fur-Mn2+-feoAB1 operator
Descriptor: DNA (25-MER), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION
Authors:Deng, Z, Chen, Z.
Deposit date:2014-09-12
Release date:2015-07-15
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator.
Nat Commun, 6
4RB1
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BU of 4rb1 by Molmil
Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Fur-Mn2+-E. coli Fur box
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*TP*AP*AP*TP*GP*AP*TP*AP*AP*TP*CP*AP*TP*TP*AP*TP*CP*CP*GP*C)-3'), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION
Authors:Deng, Z, Chen, Z.
Deposit date:2014-09-12
Release date:2015-07-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator.
Nat Commun, 6
1CR6
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BU of 1cr6 by Molmil
CRYSTAL STRUCTURE OF MURINE SOLUBLE EPOXIDE HYDROLASE COMPLEXED WITH CPU INHIBITOR
Descriptor: EPOXIDE HYDROLASE, N-CYCLOHEXYL-N'-(PROPYL)PHENYL UREA
Authors:Argiriadi, M.A, Morisseau, C, Hammock, B.D, Christianson, D.W.
Deposit date:1999-08-13
Release date:1999-11-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase.
Proc.Natl.Acad.Sci.USA, 96, 1999
7XW6
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BU of 7xw6 by Molmil
TSHR-Gs-M22 antibody-ML109 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E.
Deposit date:2022-05-26
Release date:2022-08-17
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Hormone- and antibody-mediated activation of the thyrotropin receptor.
Nature, 609, 2022
7XW5
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BU of 7xw5 by Molmil
TSHR-thyroid stimulating hormone-Gs-ML109 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Glycoprotein hormones alpha chain, ...
Authors:Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E.
Deposit date:2022-05-26
Release date:2022-08-24
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Hormone- and antibody-mediated activation of the thyrotropin receptor.
Nature, 609, 2022
7F0S
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BU of 7f0s by Molmil
A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically 1dynamic RNA-dependent RNA polymerase
Descriptor: RNA-directed RNA polymerase nsP4
Authors:Tan, Y.B, Luo, D.
Deposit date:2021-06-06
Release date:2022-02-16
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.
Nucleic Acids Res., 50, 2022

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