7TU8
| Structure of the L. blandensis dGTPase H125A mutant bound to dGTP and dATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU5
| Structure of the L. blandensis dGTPase in the apo form | Descriptor: | MAGNESIUM ION, dGTP triphosphohydrolase | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU4
| Structure of the L. blandensis dGTPase del55-58 mutant bound to Mn | Descriptor: | 1,2-ETHANEDIOL, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU0
| Structure of the L. blandensis dGTPase bound to Mn | Descriptor: | MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU1
| Structure of the L. blandensis dGTPase R37A mutant | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, dGTP triphosphohydrolase | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU6
| Structure of the L. blandensis dGTPase bound to dATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU3
| Structure of the L. blandensis dGTPase del55-58 mutant | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, SULFATE ION, ... | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU7
| Structure of the L. blandensis dGTPase H125A mutant bound to dGTP | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU2
| Structure of the L. blandensis dGTPase R37A mutant bound to Mn | Descriptor: | MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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1FHG
| HIGH RESOLUTION REFINEMENT OF TELOKIN | Descriptor: | TELOKIN | Authors: | Tomchick, D.R, Minor, W, Kiyatkin, A, Lewinski, K, Somlyo, A.V, Somlyo, A.P. | Deposit date: | 2000-08-01 | Release date: | 2000-08-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structure determination of telokin, the C-terminal domain of myosin light chain kinase, at 2.8 A resolution. J.Mol.Biol., 227, 1992
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4L1P
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4L1U
| Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide | Descriptor: | GLYCEROL, RNA polymerase-associated protein RTF1 homolog, SULFATE ION, ... | Authors: | Wier, A.D, Heroux, A, VanDemark, A.P. | Deposit date: | 2013-06-03 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.424 Å) | Cite: | Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proc.Natl.Acad.Sci.USA, 110, 2013
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8V0H
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8PVU
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6KSP
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6KZM
| GluK3 receptor complex with kainate | Descriptor: | Glutamate receptor ionotropic, kainate 3 | Authors: | Kumar, J, Kumari, J, Burada, A.P. | Deposit date: | 2019-09-24 | Release date: | 2020-03-04 | Method: | ELECTRON MICROSCOPY (9.6 Å) | Cite: | Structural dynamics of the GluK3-kainate receptor neurotransmitter binding domains revealed by cryo-EM. Int.J.Biol.Macromol., 149, 2020
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6L6F
| GluK3 receptor complex with UBP301 | Descriptor: | Glutamate receptor ionotropic, kainate 3 | Authors: | Kumar, J, Kumari, J, Burada, A.P. | Deposit date: | 2019-10-28 | Release date: | 2020-03-04 | Method: | ELECTRON MICROSCOPY (10.6 Å) | Cite: | Structural dynamics of the GluK3-kainate receptor neurotransmitter binding domains revealed by cryo-EM. Int.J.Biol.Macromol., 149, 2020
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6KSS
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4MX3
| Crystal Structure of PKA RIalpha Homodimer | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit | Authors: | Bruystens, J.G.H, Wu, J, Fortezzo, A, Kornev, A.P, Blumenthal, D.A, Taylor, S.S. | Deposit date: | 2013-09-25 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.88 Å) | Cite: | PKA RI alpha Homodimer Structure Reveals an Intermolecular Interface with Implications for Cooperative cAMP Binding and Carney Complex Disease. Structure, 22, 2014
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4L3P
| Crystal Structure of 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine bound to TAK1-TAB1 | Descriptor: | 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine, Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera | Authors: | Wang, J, Hornberger, K.R, Crew, A.P, Steinbacher, S, Maskos, K, Moertl, M. | Deposit date: | 2013-06-06 | Release date: | 2013-06-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1. Bioorg.Med.Chem.Lett., 23, 2013
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6LU9
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4NJI
| Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 6-carboxy-5,6,7,8-tetrahydropterin, and Mg2+ | Descriptor: | (6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridine-6-carboxylic acid, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | Authors: | Dowling, D.P, Bruender, N.A, Young, A.P, McCarty, R.M, Bandarian, V, Drennan, C.L. | Deposit date: | 2013-11-10 | Release date: | 2013-12-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism. Nat.Chem.Biol., 10, 2014
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4L2W
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4LFH
| Crystal Structure of 9C2 TCR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9C2 TCR delta chain, 9C2 TCR gamma chain, ... | Authors: | Uldrich, A.P, Le Nours, J, Pellicci, D.G, Gras, S, Rossjohn, J, Godfrey, D.I. | Deposit date: | 2013-06-26 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | CD1d-lipid antigen recognition by the gamma delta TCR. Nat.Immunol., 14, 2013
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4L1D
| Voltage-gated sodium channel beta3 subunit Ig domain | Descriptor: | Sodium channel subunit beta-3 | Authors: | Namadurai, S, Weimhofer, M, Rajappa, R, Stott, K, Klingauf, J, Chirgadze, D.Y, Jackson, A.P. | Deposit date: | 2013-06-03 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure and Molecular Imaging of the Nav Channel beta 3 Subunit Indicates a Trimeric Assembly. J.Biol.Chem., 289, 2014
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