5MZI
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![BU of 5mzi by Molmil](/molmil-images/mine/5mzi) | Pseudomonas fluorescens kynurenine 3-monooxygenase (KMO) in complex with 3-(5-chloro-6-cyclopropoxy-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)propanoic acid | Descriptor: | 3-(5-chloro-6-cyclopropoxy-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)propanoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Rowland, P. | Deposit date: | 2017-01-31 | Release date: | 2017-04-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis. J. Med. Chem., 60, 2017
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2HKD
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![BU of 2hkd by Molmil](/molmil-images/mine/2hkd) | |
4AAL
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![BU of 4aal by Molmil](/molmil-images/mine/4aal) | MacA wild-type oxidized | Descriptor: | ACETATE ION, CALCIUM ION, CYTOCHROME C551 PEROXIDASE, ... | Authors: | Seidel, J. | Deposit date: | 2011-12-05 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Maca is a Second Cytochrome C Peroxidase of Geobacter Sulfurreducens. Biochemistry, 51, 2012
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4AAN
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![BU of 4aan by Molmil](/molmil-images/mine/4aan) | MacA wild-type fully reduced | Descriptor: | (R,R)-2,3-BUTANEDIOL, CALCIUM ION, CYTOCHROME C551 PEROXIDASE, ... | Authors: | Seidel, J. | Deposit date: | 2011-12-05 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Maca is a Second Cytochrome C Peroxidase of Geobacter Sulfurreducens. Biochemistry, 51, 2012
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5N7T
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![BU of 5n7t by Molmil](/molmil-images/mine/5n7t) | Pseudomonas fluorescens kynurenine 3-monooxygenase (KMO) in complex with 3-(5,6-dichloro-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)propanoic acid | Descriptor: | 3-(5,6-DICHLORO-2-OXOBENZO[D]OXAZOL-3(2H)-YL)PROPANOIC ACID, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Rowland, P. | Deposit date: | 2017-02-21 | Release date: | 2017-06-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis. Bioorg. Med. Chem. Lett., 27, 2017
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6GRE
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![BU of 6gre by Molmil](/molmil-images/mine/6gre) | |
4AAO
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![BU of 4aao by Molmil](/molmil-images/mine/4aao) | MacA-H93G | Descriptor: | CALCIUM ION, CYTOCHROME C551 PEROXIDASE, HEME C, ... | Authors: | Seidel, J. | Deposit date: | 2011-12-05 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Maca is a Second Cytochrome C Peroxidase of Geobacter Sulfurreducens. Biochemistry, 51, 2012
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4AAM
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![BU of 4aam by Molmil](/molmil-images/mine/4aam) | MacA wild-type mixed-valence | Descriptor: | CALCIUM ION, CYTOCHROME C551 PEROXIDASE, HEME C, ... | Authors: | Seidel, J. | Deposit date: | 2011-12-05 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Maca is a Second Cytochrome C Peroxidase of Geobacter Sulfurreducens. Biochemistry, 51, 2012
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2FKJ
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![BU of 2fkj by Molmil](/molmil-images/mine/2fkj) | The crystal structure of engineered OspA | Descriptor: | Outer Surface Protein A | Authors: | Makabe, K, Terechko, V, Gawlak, G, Yan, S, Koide, S. | Deposit date: | 2006-01-04 | Release date: | 2006-11-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Atomic structures of peptide self-assembly mimics. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2FKG
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![BU of 2fkg by Molmil](/molmil-images/mine/2fkg) | The Crystal Structure of Engineered OspA | Descriptor: | Outer Surface Protein A | Authors: | Makabe, K, Terechko, V, Gawlak, G, Yan, S, Koide, S. | Deposit date: | 2006-01-04 | Release date: | 2006-11-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Atomic structures of peptide self-assembly mimics. Proc.Natl.Acad.Sci.Usa, 103, 2006
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4JO9
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![BU of 4jo9 by Molmil](/molmil-images/mine/4jo9) | Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex 1:2 stoichiometry | Descriptor: | Nucleoporin p54, Nucleoporin p58/p45 | Authors: | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | Deposit date: | 2013-03-18 | Release date: | 2014-09-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
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5EIR
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![BU of 5eir by Molmil](/molmil-images/mine/5eir) | Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. | Descriptor: | Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, SULFATE ION, ... | Authors: | Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. | Deposit date: | 2015-10-30 | Release date: | 2016-09-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
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5N6R
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![BU of 5n6r by Molmil](/molmil-images/mine/5n6r) | Solution structure of the Dbl-homology domain of Bcr-Abl | Descriptor: | Breakpoint cluster region protein | Authors: | Reckel, S, Lohr, F, Buchner, L, Guntert, P, Dotsch, V, Hantschel, O. | Deposit date: | 2017-02-16 | Release date: | 2017-12-27 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nat Commun, 8, 2017
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5OC7
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![BU of 5oc7 by Molmil](/molmil-images/mine/5oc7) | Crystal structure of the pleckstrin-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-PH_4). | Descriptor: | Breakpoint cluster region protein,pleckstrin-homology domain of Bcr-Abl, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ... | Authors: | Reckel, S, Reynaud, A, Pojer, F, Hantschel, O. | Deposit date: | 2017-06-29 | Release date: | 2017-12-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.652 Å) | Cite: | Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nat Commun, 8, 2017
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5N7E
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![BU of 5n7e by Molmil](/molmil-images/mine/5n7e) | Crystal structure of the Dbl-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-DH_4). | Descriptor: | Breakpoint cluster region protein, Mb(Bcr-DH_4) | Authors: | Reckel, S, Reynaud, A, Pojer, F, Hantschel, O. | Deposit date: | 2017-02-20 | Release date: | 2017-12-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.647 Å) | Cite: | Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nat Commun, 8, 2017
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5EI3
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![BU of 5ei3 by Molmil](/molmil-images/mine/5ei3) | Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. | Descriptor: | Eukaryotic translation initiation factor 4 gamma, Eukaryotic translation initiation factor 4E, SULFATE ION, ... | Authors: | Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. | Deposit date: | 2015-10-29 | Release date: | 2016-09-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
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4JO7
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![BU of 4jo7 by Molmil](/molmil-images/mine/4jo7) | Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex with 2:2 stoichiometry | Descriptor: | Nucleoporin p54, Nucleoporin p58/p45 | Authors: | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | Deposit date: | 2013-03-17 | Release date: | 2014-09-17 | Last modified: | 2016-02-03 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
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5EKV
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![BU of 5ekv by Molmil](/molmil-images/mine/5ekv) | Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. | Descriptor: | 3-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-4-oxidanyl-cyclobut-3-ene-1,2-dione, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1 | Authors: | Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. | Deposit date: | 2015-11-04 | Release date: | 2016-09-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.61 Å) | Cite: | Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
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1AMX
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5EHC
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![BU of 5ehc by Molmil](/molmil-images/mine/5ehc) | Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. | Descriptor: | 3-[[(2~{R},3~{S},4~{R},5~{R})-5-[2-azanyl-7-[(3-chlorophenyl)methyl]-6-oxidanylidene-1~{H}-purin-7-ium-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-4-oxidanyl-cyclobut-3-ene-1,2-dione, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E | Authors: | Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. | Deposit date: | 2015-10-28 | Release date: | 2016-09-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
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2I5Z
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![BU of 2i5z by Molmil](/molmil-images/mine/2i5z) | The crystal structure of OspA mutant | Descriptor: | Outer surface protein A, TETRAETHYLENE GLYCOL | Authors: | Makabe, K, Terechko, V, Koide, S. | Deposit date: | 2006-08-26 | Release date: | 2007-07-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet. J.Mol.Biol., 368, 2007
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2OXI
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![BU of 2oxi by Molmil](/molmil-images/mine/2oxi) | |
1WMR
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![BU of 1wmr by Molmil](/molmil-images/mine/1wmr) | Crystal Structure of Isopullulanase from Aspergillus niger ATCC 9642 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isopullulanase | Authors: | Mizuno, M, Tonozuka, T, Miyasaka, Y, Akeboshi, H, Kamitori, S, Nishikawa, A, Sakano, Y. | Deposit date: | 2004-07-15 | Release date: | 2005-07-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Aspergillus niger Isopullulanase, a Member of Glycoside Hydrolase Family 49 J.Mol.Biol., 376, 2008
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1X0C
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![BU of 1x0c by Molmil](/molmil-images/mine/1x0c) | Improved Crystal Structure of Isopullulanase from Aspergillus niger ATCC 9642 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isopullulanase | Authors: | Mizuno, M, Tonozuka, T, Yamamura, A, Miyasaka, Y, Akeboshi, H, Kamitori, S, Nishikawa, A, Sakano, Y. | Deposit date: | 2005-03-17 | Release date: | 2006-06-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Aspergillus niger Isopullulanase, a Member of Glycoside Hydrolase Family 49 J.Mol.Biol., 376, 2008
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2OYB
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![BU of 2oyb by Molmil](/molmil-images/mine/2oyb) | |