4ZKT
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8WQW
| Cryo-EM structure of bsAb3 Fab-Gn-Gc complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein C, Glycoprotein N, ... | Authors: | Wu, Y, Sun, J.Q. | Deposit date: | 2023-10-12 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model. Proc.Natl.Acad.Sci.USA, 121, 2024
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5K1A
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5K16
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5K1C
| Crystal structure of the UAF1/WDR20/USP12 complex | Descriptor: | PHOSPHATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Ubiquitin carboxyl-terminal hydrolase 12, ... | Authors: | Li, H, D'Andrea, A.D, Zheng, N. | Deposit date: | 2016-05-18 | Release date: | 2016-07-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20. Mol.Cell, 63, 2016
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5K1B
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3JAY
| Atomic model of transcribing cytoplasmic polyhedrosis virus | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Capsid protein VP1, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Yu, X.K, Jiang, J.S, Sun, J.C, Zhou, Z.H. | Deposit date: | 2015-07-06 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A putative ATPase mediates RNA transcription and capping in a dsRNA virus. Elife, 4, 2015
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3JB1
| Atomic model of cytoplasmic polyhedrosis virus with SAM | Descriptor: | Capsid protein VP1, S-ADENOSYLMETHIONINE, Structural protein VP3, ... | Authors: | Yu, X.K, Jiang, J.S, Sun, J.C, Zhou, Z.H. | Deposit date: | 2015-07-06 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A putative ATPase mediates RNA transcription and capping in a dsRNA virus. Elife, 4, 2015
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3JB2
| Atomic model of cytoplasmic polyhedrosis virus with SAM and GTP | Descriptor: | Capsid protein VP1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Yu, X.K, Jiang, J.S, Sun, J.C, Zhou, Z.H. | Deposit date: | 2015-07-06 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A putative ATPase mediates RNA transcription and capping in a dsRNA virus. Elife, 4, 2015
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3JB0
| Atomic model of cytoplasmic polyhedrosis virus with GTP | Descriptor: | Capsid protein VP1, GUANOSINE-5'-TRIPHOSPHATE, Structural protein VP3, ... | Authors: | Yu, X.K, Jiang, J.S, Sun, J.C, Zhou, Z.H. | Deposit date: | 2015-07-06 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A putative ATPase mediates RNA transcription and capping in a dsRNA virus. Elife, 4, 2015
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3JB3
| Atomic model of cytoplasmic polyhedrosis virus with SAM, GTP and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Capsid protein VP1, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Yu, X.K, Jiang, J.S, Sun, J.C, Zhou, Z.H. | Deposit date: | 2015-07-06 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A putative ATPase mediates RNA transcription and capping in a dsRNA virus. Elife, 4, 2015
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5K19
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3JAZ
| Atomic model of cytoplasmic polyhedrosis virus with ATP | Descriptor: | Capsid protein VP1, Structural protein VP3, Viral structural protein 5 | Authors: | Yu, X.K, Jiang, J.S, Sun, J.C, Zhou, Z.H. | Deposit date: | 2015-07-06 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A putative ATPase mediates RNA transcription and capping in a dsRNA virus. Elife, 4, 2015
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6TY9
| In situ structure of BmCPV RNA dependent RNA polymerase at initiation state | Descriptor: | MAGNESIUM ION, Non-template RNA (5'-D(*(GTA))-R(P*GP*UP*AP*AP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), RNA-dependent RNA Polymerase, ... | Authors: | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | Deposit date: | 2019-08-08 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat.Struct.Mol.Biol., 26, 2019
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6TZ1
| In situ structure of BmCPV RNA-dependent RNA polymerase at early-elongation state | Descriptor: | Non-template RNA (5'-D(*(GTA))-R(P*GP*UP*A)-3'), RNA-dependent RNA Polymerase, Template RNA (5'-R(P*AP*GP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | Authors: | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | Deposit date: | 2019-08-09 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat.Struct.Mol.Biol., 26, 2019
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6TY8
| In situ structure of BmCPV RNA dependent RNA polymerase at quiescent state | Descriptor: | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-dependent RNA Polymerase, Viral structural protein 4 | Authors: | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | Deposit date: | 2019-08-08 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat.Struct.Mol.Biol., 26, 2019
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6E3M
| The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(3-carboxyphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | Descriptor: | 1,2-ETHANEDIOL, 6-(3-carboxyphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, ... | Authors: | Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. | Deposit date: | 2018-07-14 | Release date: | 2019-07-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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6E3N
| The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-4-oxo-6-(o-tolyl)-1,4-dihydropyridine-2-carboxylic acid | Descriptor: | 3-hydroxy-6-(2-methylphenyl)-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein | Authors: | Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. | Deposit date: | 2018-07-14 | Release date: | 2019-07-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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6E3O
| The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | Descriptor: | 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein | Authors: | Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. | Deposit date: | 2018-07-14 | Release date: | 2019-07-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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6E3P
| The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(3-(1H-tetrazol-5-yl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | Descriptor: | 3-hydroxy-4-oxo-6-[3-(1H-tetrazol-5-yl)phenyl]-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein | Authors: | Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. | Deposit date: | 2018-07-14 | Release date: | 2019-07-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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6TZ2
| In situ structure of BmCPV RNA-dependent RNA polymerase at elongation state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-template RNA (36-MER), ... | Authors: | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | Deposit date: | 2019-08-09 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat.Struct.Mol.Biol., 26, 2019
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6TZ0
| In situ structure of BmCPV RNA-dependent RNA polymerase at abortive state | Descriptor: | RNA-dependent RNA Polymerase, Viral structural protein 4 | Authors: | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | Deposit date: | 2019-08-09 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat.Struct.Mol.Biol., 26, 2019
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6E6W
| The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-6-(2-methyl-4-(1H-tetrazol-5-yl)phenyl)-4-oxo-1,4-dihydropyridine-2-carboxylic acid | Descriptor: | 3-hydroxy-6-[2-methyl-4-(1H-tetrazol-5-yl)phenyl]-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein | Authors: | Dick, B.L, Morrison, C.N, Credille, C.V, Cohen, S.M. | Deposit date: | 2018-07-25 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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6E6X
| The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 1-(4-(1H-tetrazol-5-yl)phenyl)-5-hydroxy-2-methylpyridin-4(1H)-one | Descriptor: | 1,2-ETHANEDIOL, 5-hydroxy-2-methyl-1-[4-(1H-tetrazol-5-yl)phenyl]pyridin-4(1H)-one, MANGANESE (II) ION, ... | Authors: | Dick, B.L, Morrison, C.N, Credille, C.V, Cohen, S.M. | Deposit date: | 2018-07-25 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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6E4C
| The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-6-(2-methyl-4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)-4-oxo-1,4-dihydropyridine-2-carboxylic acid | Descriptor: | 1,2-ETHANEDIOL, 3-hydroxy-6-[2-methyl-4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl]-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, ... | Authors: | Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. | Deposit date: | 2018-07-17 | Release date: | 2019-07-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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