6KG8
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![BU of 6kg8 by Molmil](/molmil-images/mine/6kg8) | Solution structure of CaCohA2 from Clostridium acetobutylicum | Descriptor: | Probably cellulosomal scaffolding protein, secreted cellulose-binding and cohesin domain | Authors: | Feng, Y, Yao, X. | Deposit date: | 2019-07-11 | Release date: | 2020-07-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules. Sci Adv, 6, 2020
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6KPF
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![BU of 6kpf by Molmil](/molmil-images/mine/6kpf) | Cryo-EM structure of a class A GPCR with G protein complex | Descriptor: | 7-[(6aR,9R,10aR)-1-Hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl]- 7-methyloctanenitrile, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Li, X.T, Hua, T, Wu, L.J, Makriyannis, A, Shen, L, Wang, Y.X, Liu, Z.J. | Deposit date: | 2019-08-15 | Release date: | 2020-02-12 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-GiComplex Structures. Cell, 180, 2020
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6KPG
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![BU of 6kpg by Molmil](/molmil-images/mine/6kpg) | Cryo-EM structure of CB1-G protein complex | Descriptor: | (6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Hua, T, Li, X.T, Wu, L.J, Makriyannis, A, Wang, Y.X, Shen, L, Liu, Z.J. | Deposit date: | 2019-08-15 | Release date: | 2020-02-12 | Last modified: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-GiComplex Structures. Cell, 180, 2020
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3CN6
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![BU of 3cn6 by Molmil](/molmil-images/mine/3cn6) | Crystal structure of the Spinach Aquaporin SoPIP2;1 S274E mutant | Descriptor: | Aquaporin, CADMIUM ION | Authors: | Nyblom, M, Alfredsson, A, Hallgren, K, Hedfalk, K, Neutze, R, Tornroth-Horsefield, S. | Deposit date: | 2008-03-25 | Release date: | 2009-02-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating. J.Mol.Biol., 387, 2009
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3EAE
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![BU of 3eae by Molmil](/molmil-images/mine/3eae) | PWWP domain of human hepatoma-derived growth factor 2 (HDGF2) | Descriptor: | Hepatoma-derived growth factor-related protein 2 | Authors: | Amaya, M.F, Zeng, H, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-08-25 | Release date: | 2008-09-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural and Histone Binding Ability Characterizations of Human PWWP Domains. Plos One, 6, 2011
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8I39
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![BU of 8i39 by Molmil](/molmil-images/mine/8i39) | Cryo-EM structure of abscisic acid transporter AtABCG25 with ABA | Descriptor: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ABC transporter G family member 25 | Authors: | Huang, X, Zhang, X, Zhang, P. | Deposit date: | 2023-01-16 | Release date: | 2023-09-13 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25. Nat.Plants, 9, 2023
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8I3D
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8I3B
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8I3C
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8I38
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8I3A
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6ATH
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![BU of 6ath by Molmil](/molmil-images/mine/6ath) | Cdk2/cyclin A/p27-KID-deltaC | Descriptor: | Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B, ... | Authors: | White, S.W, Yun, M. | Deposit date: | 2017-08-29 | Release date: | 2018-09-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation. Nat Commun, 10, 2019
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8IEM
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![BU of 8iem by Molmil](/molmil-images/mine/8iem) | Cryo-EM structure of ATP13A2 in the E2P state | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ... | Authors: | Liu, Z.M, Mu, J.Q, Xue, C.Y. | Deposit date: | 2023-02-15 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Conformational cycle of human polyamine transporter ATP13A2. Nat Commun, 14, 2023
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8IES
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![BU of 8ies by Molmil](/molmil-images/mine/8ies) | Cryo-EM structure of ATP13A2 in the E1P-ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ... | Authors: | Liu, Z.M, Mu, J.Q, Xue, C.Y. | Deposit date: | 2023-02-15 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Conformational cycle of human polyamine transporter ATP13A2. Nat Commun, 14, 2023
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8IEN
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![BU of 8ien by Molmil](/molmil-images/mine/8ien) | Cryo-EM structure of ATP13A2 in the E2-Pi state | Descriptor: | MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ... | Authors: | Liu, Z.M, Mu, J.Q, Xue, C.Y. | Deposit date: | 2023-02-15 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Conformational cycle of human polyamine transporter ATP13A2. Nat Commun, 14, 2023
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8IEO
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![BU of 8ieo by Molmil](/molmil-images/mine/8ieo) | Cryo-EM structure of ATP13A2 in the nominal E1P state | Descriptor: | MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ... | Authors: | Liu, Z.M, Mu, J.Q, Xue, C.Y. | Deposit date: | 2023-02-15 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Conformational cycle of human polyamine transporter ATP13A2. Nat Commun, 14, 2023
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8IER
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6B0T
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8IEL
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8IEK
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8IND
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![BU of 8ind by Molmil](/molmil-images/mine/8ind) | Crystal structure of UGT74AN3-UDP-RES | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-[(1R,2S,4R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-6-yl]pyran-2-one, Glycosyltransferase, ... | Authors: | Huang, W. | Deposit date: | 2023-03-09 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3 Acs Catalysis, 14, 2024
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8INV
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![BU of 8inv by Molmil](/molmil-images/mine/8inv) | Crystal structure of UGT74AN3-UDP-BUF | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Long, F, Huang, W. | Deposit date: | 2023-03-10 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3 Acs Catalysis, 14, 2024
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8INA
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![BU of 8ina by Molmil](/molmil-images/mine/8ina) | Crystal structure of UGT74AN3-UDP | Descriptor: | GLYCEROL, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE | Authors: | Long, F, Huang, W. | Deposit date: | 2023-03-09 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3 Acs Catalysis, 14, 2024
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6M8Q
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![BU of 6m8q by Molmil](/molmil-images/mine/6m8q) | Cleavage and Polyadenylation Specificity Factor Subunit 3 (CPSF3) in complex with NVP-LTM531 | Descriptor: | Cleavage and polyadenylation specificity factor subunit 3, N-{3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzene-1-carbonyl}-L-phenylalanine, PHOSPHATE ION, ... | Authors: | Weihofen, W.A, Salcius, M, Michaud, G. | Deposit date: | 2018-08-22 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. Nat.Chem.Biol., 16, 2020
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8INO
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![BU of 8ino by Molmil](/molmil-images/mine/8ino) | Crystal structure of UGT74AN3 in complex UDP and PER | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(3S,5S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3,5,14-tris(oxidanyl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, Glycosyltransferase, ... | Authors: | Long, F, Huang, W. | Deposit date: | 2023-03-10 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3 Acs Catalysis, 14, 2024
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