6ATH

Cdk2/cyclin A/p27-KID-deltaC

Summary for 6ATH

• Entry DOI: 10.2210/pdb6ath/pdb
• Descriptor: Cyclin-dependent kinase 2, Cyclin-A2, Cyclin-dependent kinase inhibitor 1B, ... (5 entities in total)
• Functional Keywords: inhibitor, complex, idp, cdk, cyclin, kinase, phosphortlation, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 72545.48

Authors

White, S.W.,Yun, M. (deposition date: 2017-08-29, release date: 2018-09-12, Last modification date: 2023-10-04)

• Primary citation: Tsytlonok, M.,Sanabria, H.,Wang, Y.,Felekyan, S.,Hemmen, K.,Phillips, A.H.,Yun, M.K.,Waddell, M.B.,Park, C.G.,Vaithiyalingam, S.,Iconaru, L.,White, S.W.,Tompa, P.,Seidel, C.A.M.,Kriwacki, R.; Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation.; Nat Commun, 10:1676-1676, 2019; PubMed: 30976006; DOI: 10.1038/s41467-019-09446-w

Experimental method

X-RAY DIFFRACTION (1.82 Å)