3URA
| Crystal Structure of PTE mutant H254G/H257W/L303T/K185R/I274N/A80V/S61T | Descriptor: | COBALT (II) ION, IMIDAZOLE, Parathion hydrolase | Authors: | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | Deposit date: | 2011-11-21 | Release date: | 2012-08-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry, 51, 2012
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3URN
| Crystal Structure of PTE mutant H254G/H257W/L303T/K185R/I274N/A80V/S61T with cyclohexyl methylphosphonate inhibitor | Descriptor: | COBALT (II) ION, IMIDAZOLE, Parathion hydrolase, ... | Authors: | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | Deposit date: | 2011-11-22 | Release date: | 2012-08-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry, 51, 2012
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3UR5
| Crystal Structure of PTE mutant K185R/I274N | Descriptor: | COBALT (II) ION, DIETHYL HYDROGEN PHOSPHATE, Parathion hydrolase | Authors: | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | Deposit date: | 2011-11-21 | Release date: | 2012-08-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry, 51, 2012
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3URQ
| Crystal Structure of PTE mutant H254G/H257W/L303T/M317L/I106C/F132I/L271I/K185R/I274N/A80V/R67H with cyclohexyl methylphosphonate inhibitor | Descriptor: | COBALT (II) ION, IMIDAZOLE, Parathion hydrolase, ... | Authors: | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | Deposit date: | 2011-11-22 | Release date: | 2012-08-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry, 51, 2012
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3URB
| Crystal Structure of PTE mutant H254G/H257W/L303T/M317L/I106C/F132I/L271I/K185R/I274N/A80V/R67H | Descriptor: | COBALT (II) ION, DIETHYL HYDROGEN PHOSPHATE, IMIDAZOLE, ... | Authors: | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | Deposit date: | 2011-11-21 | Release date: | 2012-08-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry, 51, 2012
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3LET
| Crystal Structure of Fic domain containing AMPylator, VopS | Descriptor: | Adenosine monophosphate-protein transferase vopS | Authors: | Luong, P.H, Kinch, L.N, Brautigam, C.A, Grishin, N.V, Tomchick, D.R, Orth, K. | Deposit date: | 2010-01-15 | Release date: | 2010-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Structural and Kinetic Analysis of VopS with Fic Domain Supports a Direct Transfer Mechanism for AMPylation To be Published
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7MWI
| Crystal structure of human BAZ2A | Descriptor: | Bromodomain adjacent to zinc finger domain protein 2A, UNKNOWN ATOM OR ION | Authors: | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-17 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status. J.Biol.Chem., 297, 2021
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3UPM
| Crystal Structure of PTE mutant H254Q/H257F/K185R/I274N | Descriptor: | COBALT (II) ION, Parathion hydrolase | Authors: | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | Deposit date: | 2011-11-18 | Release date: | 2012-08-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry, 51, 2012
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4LIP
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2ZFY
| Crystal structure of human Otubain 1 | Descriptor: | Ubiquitin thioesterase OTUB1 | Authors: | Akutsu, M, Walker, J.R, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-01-16 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural basis and specificity of human otubain 1-mediated deubiquitination. Biochem.J., 418, 2009
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3C2H
| Crystal Structure of SYS-1 at 2.6A resolution | Descriptor: | CITRATE ANION, GLYCEROL, Sys-1 protein | Authors: | Liu, J, Phillips, B.T, Amaya, M.F, Kimble, J, Xu, W. | Deposit date: | 2008-01-25 | Release date: | 2008-05-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The C. elegans SYS-1 protein is a bona fide beta-catenin. Dev.Cell, 14, 2008
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8JVB
| Cryo-EM structure of the Type II secretion system protein from Acidithiobacillus caldus | Descriptor: | Type II and III secretion system protein | Authors: | Liu, R.H, Zhang, K, Feng, Q.S, Dai, X, Fu, Y, Li, Y. | Deposit date: | 2023-06-28 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.39 Å) | Cite: | Cryo-EM structure of the Type II secretion system protein from Acidithiobacillus caldus To Be Published
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3C2G
| Crystal complex of SYS-1/POP-1 at 2.5A resolution | Descriptor: | Pop-1 8-residue peptide, Sys-1 protein | Authors: | Liu, J, Phillips, B.T, Amaya, M.F, Kimble, J, Xu, W. | Deposit date: | 2008-01-24 | Release date: | 2008-05-20 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The C. elegans SYS-1 protein is a bona fide beta-catenin. Dev.Cell, 14, 2008
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2FXO
| Structure of the human beta-myosin S2 fragment | Descriptor: | Myosin heavy chain, cardiac muscle beta isoform | Authors: | Blankenfeldt, W, Thoma, N.H, Wray, J.S, Gautel, M, Schlichting, I. | Deposit date: | 2006-02-06 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of human cardiac {beta}-myosin II S2-{Delta} provide insight into the functional role of the S2 subfragment Proc.Natl.Acad.Sci.Usa, 103, 2006
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2FXM
| Structure of the human beta-myosin S2 fragment | Descriptor: | MERCURY (II) ION, Myosin heavy chain, cardiac muscle beta isoform | Authors: | Blankenfeldt, W, Thoma, N.H, Wray, J.S, Gautel, M, Schlichting, I. | Deposit date: | 2006-02-06 | Release date: | 2006-11-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of human cardiac {beta}-myosin II S2-{Delta} provide insight into the functional role of the S2 subfragment Proc.Natl.Acad.Sci.Usa, 103, 2006
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3QWP
| Crystal structure of SET and MYND domain containing 3; Zinc finger MYND domain-containing protein 1 | Descriptor: | GLYCEROL, S-ADENOSYLMETHIONINE, SET and MYND domain-containing protein 3, ... | Authors: | Dong, A, Dombrovski, L, Li, Y, Wernimont, A, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2011-02-28 | Release date: | 2011-04-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | The Crystal Structure of human Histone-lysine N-methyltransferase SMYD3 To be Published
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3UXG
| Crystal structure of RFXANK | Descriptor: | DNA-binding protein RFXANK, Histone deacetylase 4, UNKNOWN ATOM OR ION | Authors: | Tempel, W, Chao, X, Bian, C, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2011-12-05 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
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7VQO
| Cryo-EM structure of Ams1 bound to the FW domain of Nbr1 | Descriptor: | Ams1, Nbr1 and malE fusion protein, ZINC ION | Authors: | Zhang, J, Ye, K. | Deposit date: | 2021-10-20 | Release date: | 2022-07-06 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.19 Å) | Cite: | Structural mechanism of protein recognition by the FW domain of autophagy receptor Nbr1 Nat Commun, 13, 2022
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7WMD
| PQQ-dependent alcohol dehydrogenase detoxifying DON | Descriptor: | CALCIUM ION, PQQ-dependent alcohol dehydrogenase | Authors: | Chen, M, Yang, H, Lv, F. | Deposit date: | 2022-01-14 | Release date: | 2022-09-07 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Function Analysis of a Quinone-Dependent Dehydrogenase Capable of Deoxynivalenol Detoxification. J.Agric.Food Chem., 70, 2022
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7WMK
| PQQ-dependent alcohol dehydrogenase complexed with PQQ | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, CALCIUM ION, ... | Authors: | Chen, M, Yang, H, Lv, F. | Deposit date: | 2022-01-15 | Release date: | 2022-09-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structure-Function Analysis of a Quinone-Dependent Dehydrogenase Capable of Deoxynivalenol Detoxification. J.Agric.Food Chem., 70, 2022
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7VYX
| Crystal structure of the selenomethionine(SeMet)-derived Cas12c1 (D969A) ternary complex | Descriptor: | Non-target DNA strand, Selenomethionine (SeMet)-labeled Cas12c1 D969A mutant, Target DNA strand, ... | Authors: | Zhang, B, Lin, J.Y, Perculija, V, OuYang, S.Y. | Deposit date: | 2021-11-15 | Release date: | 2022-11-02 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system Nucleic Acids Res., 50, 2022
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7XMV
| E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A(AMP/ADP) filament bound with ADP, AMP and R5P | Descriptor: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | Deposit date: | 2022-04-27 | Release date: | 2022-06-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Filamentation modulates allosteric regulation of PRPS. Elife, 11, 2022
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7XN3
| E.coli phosphoribosylpyrophosphate (PRPP) synthetase type B filament bound with Pi | Descriptor: | PHOSPHATE ION, Ribose-phosphate pyrophosphokinase | Authors: | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | Deposit date: | 2022-04-27 | Release date: | 2022-06-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Filamentation modulates allosteric regulation of PRPS. Elife, 11, 2022
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7XMU
| E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P | Descriptor: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | Deposit date: | 2022-04-26 | Release date: | 2022-06-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Filamentation modulates allosteric regulation of PRPS. Elife, 11, 2022
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7X6T
| Discovery of Selective BRD4 BD1 Inhibitor Based on [1,2,4] triazolo [4,3-b] pyridazine Scaffold | Descriptor: | (2~{R})-2-[[3-methyl-6-(2-phenoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]amino]propanamide, Isoform C of Bromodomain-containing protein 4 | Authors: | Cao, D, Xiong, B. | Deposit date: | 2022-03-08 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Discovery of Selective BRD4 BD1 Inhibitor Based on [1,2,4] triazolo [4,3-b] pyridazine Scaffold To Be Published
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