Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7AKC
DownloadVisualize
BU of 7akc by Molmil
Structure of the of AcylTransferase domain of phenolphthiocerol/phtiocerol synthase A from Mycobacterium bovis (BCG)
Descriptor: Phenolpthiocerol synthesis type-I polyketide synthase ppsA, SODIUM ION
Authors:Brison, Y, Nahoum, V, Mourey, L, Maveyraud, L.
Deposit date:2020-09-30
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases.
Acs Chem.Biol., 15, 2020
3K1Y
DownloadVisualize
BU of 3k1y by Molmil
X-ray structure of oxidoreductase from corynebacterium diphtheriae. orthorombic crystal form, northeast structural genomics consortium target cdr100d
Descriptor: SULFATE ION, oxidoreductase
Authors:Kuzin, A, Lew, S, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-09-29
Release date:2009-10-20
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Northeast Structural Genomics Consortium Target CdR100D
To be Published
3K3N
DownloadVisualize
BU of 3k3n by Molmil
Crystal structure of the catalytic core domain of human PHF8
Descriptor: FE (II) ION, PHD finger protein 8
Authors:Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z.
Deposit date:2009-10-03
Release date:2010-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into a novel histone demethylase PHF8
Cell Res., 20, 2010
6ETY
DownloadVisualize
BU of 6ety by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor JHU3371
Descriptor: (2~{S})-2-[[(2~{R})-4-methyl-1-oxidanyl-1-oxidanylidene-pentan-2-yl]carbamoyloxy]pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barinka, C, Novakova, Z, Motlova, L.
Deposit date:2017-10-27
Release date:2018-11-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
Bioorg.Med.Chem., 27, 2019
3JA4
DownloadVisualize
BU of 3ja4 by Molmil
RNA-dependent RNA polymerases of transcribing cypoviruses
Descriptor: RNA-dependent RNA polymerase
Authors:Liu, H, Cheng, L.
Deposit date:2015-04-20
Release date:2015-10-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM shows the polymerase structures and a nonspooled genome within a dsRNA virus.
Science, 349, 2015
7AGU
DownloadVisualize
BU of 7agu by Molmil
Structure of the S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis acylated with MethylMalonyl-coenzyme A
Descriptor: 1,2-ETHANEDIOL, METHYLMALONIC ACID, Mycocerosic acid synthase
Authors:Brison, Y, Mourey, L, Maveyraud, L.
Deposit date:2020-09-23
Release date:2020-12-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases.
Acs Chem.Biol., 15, 2020
3JC7
DownloadVisualize
BU of 3jc7 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
Descriptor: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
Authors:Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
Deposit date:2015-11-24
Release date:2016-02-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
3J6Q
DownloadVisualize
BU of 3j6q by Molmil
Identification of the active sites in the methyltransferases of a transcribing dsRNA virus
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, Structural protein VP3
Authors:Zhu, B, Yang, C, Liu, H, Cheng, L, Song, F, Zeng, S, Huang, X, Ji, G, Zhu, P.
Deposit date:2014-03-20
Release date:2014-10-08
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Identification of the active sites in the methyltransferases of a transcribing dsRNA virus.
J.Mol.Biol., 426, 2014
7AGT
DownloadVisualize
BU of 7agt by Molmil
Structure of the S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis acylated with Malonyl-coenzyme A
Descriptor: MALONIC ACID, Mycocerosic acid synthase
Authors:Brison, Y, Mourey, L, Maveyraud, L.
Deposit date:2020-09-23
Release date:2020-12-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases.
Acs Chem.Biol., 15, 2020
3JSR
DownloadVisualize
BU of 3jsr by Molmil
X-Ray structure of All0216 protein from Nostoc sp. PCC 7120 at the resolution 1.8A. Northeast Structural Genomics Consortium target NsR236
Descriptor: All0216 protein, POTASSIUM ION
Authors:Kuzin, A.P, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-09-10
Release date:2009-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-Ray structure of All0216 protein from Nostoc sp. PCC 7120 at the resolution 1.8A
To be Published
4UWF
DownloadVisualize
BU of 4uwf by Molmil
Discovery of (2S)-8-((3R)-3-Methylmorpholin-4-yl)-1-(3-methyl-2-oxo- butyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido(1,2-a)pyrimidin-6- one: a Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors
Descriptor: (8S)-9-[3,5-bis(fluoranyl)phenyl]-2-morpholin-4-yl-8-(trifluoromethyl)-7,8-dihydro-6H-pyrimido[1,2-a]pyrimidin-4-one, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3
Authors:Pasquier, B, El-Ahmad, Y, Filoche-Romme, B, Dureuil, C, Fassy, F, Abecassis, P.Y, Mathieu, M, Bertrand, T, Benard, T, Barriere, C, ElBatti, S, Letallec, J.P, Sonnefraud, V, Brollo, M, Delbarre, L, Loyau, V, Pilorge, F, Bertin, L, Richepin, P, Arigon, J, Labrosse, J.R, Clement, J, Durand, F, Combet, R, Perraut, P, Leroy, V, Gay, F, Lefrancois, D, Bretin, F, Marquette, J.P, Michot, N, Caron, A, Castell, C, Schio, L, McCort, G, Goulaouic, H, Garcia-Echeverria, C, Ronan, B.
Deposit date:2014-08-12
Release date:2014-11-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Discovery of (2S)-8-[(3R)-3-Methylmorpholin-4-Yl]-1-(3-Methyl-2-Oxobutyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido[1,2-A]Pyrimidin-6-One: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors.
J.Med.Chem., 58, 2015
3K6I
DownloadVisualize
BU of 3k6i by Molmil
Crystal structure of chicken T-cadherin EC1
Descriptor: T-cadherin, ZINC ION
Authors:Shapiro, L, Ciatto, C.
Deposit date:2009-10-08
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:T-cadherin structures reveal a novel adhesive binding mechanism
Nat.Struct.Mol.Biol., 17, 2010
3K92
DownloadVisualize
BU of 3k92 by Molmil
Crystal structure of a E93K mutant of the majour Bacillus subtilis glutamate dehydrogenase RocG
Descriptor: DI(HYDROXYETHYL)ETHER, NAD-specific glutamate dehydrogenase
Authors:Gunka, K, Newman, J.A, Commichau, F.M, Herzberg, C, Rodrigues, C, Hewitt, L, Lewis, R.J, Stulke, J.
Deposit date:2009-10-15
Release date:2010-06-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties
J.Mol.Biol., 400, 2010
3K9Z
DownloadVisualize
BU of 3k9z by Molmil
Rational Design of a Structural and Functional Nitric Oxide Reductase
Descriptor: FE (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Yeung, N, Lin, Y.-W, Gao, Y.-G, Zhao, X, Russell, B.S, Lei, L, Miner, K.D, Robinson, H, Lu, Y.
Deposit date:2009-10-16
Release date:2009-12-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Rational design of a structural and functional nitric oxide reductase.
Nature, 462, 2009
3JS3
DownloadVisualize
BU of 3js3 by Molmil
Crystal structure of type I 3-dehydroquinate dehydratase (aroD) from Clostridium difficile with covalent reaction intermediate
Descriptor: 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, 3-dehydroquinate dehydratase
Authors:Minasov, G, Light, S.H, Shuvalova, L, Dubrovska, I, Winsor, J, Peterson, S.N, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-09-09
Release date:2009-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates.
J.Biol.Chem., 286, 2011
6FE5
DownloadVisualize
BU of 6fe5 by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) - the E424M inactive mutant, in complex with a inhibitor JHU 2249
Descriptor: (2~{S})-2-[[(2~{S})-4-methyl-1-oxidanyl-1-oxidanylidene-pentan-2-yl]carbamoylamino]pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barinka, C, Novakova, Z, Motlova, L.
Deposit date:2017-12-29
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
Bioorg.Med.Chem., 27, 2019
4UWG
DownloadVisualize
BU of 4uwg by Molmil
Discovery of (2S)-8-((3R)-3-Methylmorpholin-4-yl)-1-(3-methyl-2-oxo- butyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido(1,2-a)pyrimidin-6- one: a Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors
Descriptor: (8S)-2-(morpholin-4-yl)-9-[2-(propan-2-yloxy)ethyl]-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3, SULFATE ION
Authors:Pasquier, B, El-Ahmad, Y, Filoche-Romme, B, Dureuil, C, Fassy, F, Abecassis, P.Y, Mathieu, M, Bertrand, T, Benard, T, Barriere, C, ElBatti, S, Letallec, J.P, Sonnefraud, V, Brollo, M, Delbarre, L, Loyau, V, Pilorge, F, Bertin, L, Richepin, P, Arigon, J, Labrosse, J.R, Clement, J, Durand, F, Combet, R, Perraut, P, Leroy, V, Gay, F, Lefrancois, D, Bretin, F, Marquette, J.P, Michot, N, Caron, A, Castell, C, Schio, L, McCort, G, Goulaouic, H, Garcia-Echeverria, C, Ronan, B.
Deposit date:2014-08-12
Release date:2014-11-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of (2S)-8-[(3R)-3-Methylmorpholin-4-Yl]-1-(3-Methyl-2-Oxobutyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido[1,2-A]Pyrimidin-6-One: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors.
J.Med.Chem., 58, 2015
3K2V
DownloadVisualize
BU of 3k2v by Molmil
Structure of the CBS pair of a putative D-arabinose 5-phosphate isomerase from Klebsiella pneumoniae subsp. pneumoniae.
Descriptor: CYTIDINE 5'-MONOPHOSPHATE 3-DEOXY-BETA-D-GULO-OCT-2-ULO-PYRANOSONIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Cuff, M.E, Volkart, L, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-09-30
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the CBS pair of a putative D-arabinose 5-phosphate isomerase from Klebsiella pneumoniae subsp. pneumoniae.
TO BE PUBLISHED
6F5L
DownloadVisualize
BU of 6f5l by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor JHU2379
Descriptor: (2~{S})-2-[[(2~{S})-4-methyl-1-oxidanyl-1-oxidanylidene-pentan-2-yl]carbamoyloxy]pentanedioic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barinka, C, Novakova, Z, Motlova, L.
Deposit date:2017-12-01
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
Bioorg.Med.Chem., 27, 2019
3K5R
DownloadVisualize
BU of 3k5r by Molmil
Crystal Structure of mouse T-cadherin EC1 EC2
Descriptor: Cadherin 13
Authors:Shapiro, L, Ciatto, C.
Deposit date:2009-10-07
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:T-cadherin structures reveal a novel adhesive binding mechanism
Nat.Struct.Mol.Biol., 17, 2010
3K5Y
DownloadVisualize
BU of 3k5y by Molmil
Crystal structure of FBF-2/gld-1 FBEa complex
Descriptor: 5'-R(*UP*GP*UP*GP*CP*CP*AP*UP*A)-3', Fem-3 mRNA-binding factor 2
Authors:Wang, Y, Opperman, L, Wickens, M, Hall, T.M.T.
Deposit date:2009-10-08
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
3K6D
DownloadVisualize
BU of 3k6d by Molmil
Crystal structure of Xenopus laevis T-cadherin EC1
Descriptor: T-cadherin, ZINC ION
Authors:Shapiro, L, Ciatto, C.
Deposit date:2009-10-08
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:T-cadherin structures reveal a novel adhesive binding mechanism
Nat.Struct.Mol.Biol., 17, 2010
3JT0
DownloadVisualize
BU of 3jt0 by Molmil
Crystal Structure of the C-terminal fragment (426-558) Lamin-B1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR5546A
Descriptor: Lamin-B1
Authors:Kuzin, A, Abashidze, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-09-11
Release date:2009-09-22
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.392 Å)
Cite:Northeast Structural Genomics Consortium Target HR5546A
To be Published
8C8T
DownloadVisualize
BU of 8c8t by Molmil
cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with bNAbs EPTC112 and 3BNC117
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Baquero, E, Molinos-Albert, L, Mouquet, H.
Deposit date:2023-01-21
Release date:2023-07-05
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller.
Cell Host Microbe, 31, 2023
3JZI
DownloadVisualize
BU of 3jzi by Molmil
Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazole series
Descriptor: 7-amino-2-[(2-chlorobenzyl)amino]-1-{[(1S,2S)-2-hydroxycycloheptyl]methyl}-1H-benzimidazole-5-carboxamide, Biotin carboxylase
Authors:Cheng, C, Shipps, G.W, Yang, Z, Sun, B, Kawahata, N, Soucy, K, Soriano, A, Orth, P, Xiao, L, Mann, P, Black, T.
Deposit date:2009-09-23
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Discovery and optimization of antibacterial AccC inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009

223532

PDB entries from 2024-08-07

PDB statisticsPDBj update infoContact PDBjnumon