2PI0
Crystal Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-B enhancer
Summary for 2PI0
Entry DOI | 10.2210/pdb2pi0/pdb |
Descriptor | PRDIII-I region of human interferon-B promoter strand 1, PRDIII-I region of human interferon-B promoter strand 2, Interferon regulatory factor 3, ... (4 entities in total) |
Functional Keywords | interferon, protein-dna complex, transcription, transcription activator-dna complex, transcription activator/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: 2PI0 |
Total number of polymer chains | 6 |
Total formula weight | 73272.20 |
Authors | Escalante, C.R.,Nistal-Villan, E.,Leyi, S.,Garcia-Sastre, A.,Aggarwal, A.K. (deposition date: 2007-04-12, release date: 2007-10-30, Last modification date: 2023-08-30) |
Primary citation | Escalante, C.R.,Nistal-Villan, E.,Shen, L.,Garcia-Sastre, A.,Aggarwal, A.K. Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. Mol.Cell, 26:703-716, 2007 Cited by PubMed: 17560375DOI: 10.1016/j.molcel.2007.04.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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