2PI0

Crystal Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-B enhancer

Summary for 2PI0

Entry DOI	10.2210/pdb2pi0/pdb
Descriptor	PRDIII-I region of human interferon-B promoter strand 1, PRDIII-I region of human interferon-B promoter strand 2, Interferon regulatory factor 3, ... (4 entities in total)
Functional Keywords	interferon, protein-dna complex, transcription, transcription activator-dna complex, transcription activator/dna
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: 2PI0
Total number of polymer chains	6
Total formula weight	73272.20
Authors	Escalante, C.R.,Nistal-Villan, E.,Leyi, S.,Garcia-Sastre, A.,Aggarwal, A.K. (deposition date: 2007-04-12, release date: 2007-10-30, Last modification date: 2023-08-30)
Primary citation	Escalante, C.R.,Nistal-Villan, E.,Shen, L.,Garcia-Sastre, A.,Aggarwal, A.K. Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. Mol.Cell, 26:703-716, 2007 Cited by PubMed: 17560375 DOI: 10.1016/j.molcel.2007.04.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.31 Å)

Structure validation