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2PI0

Crystal Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-B enhancer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E)
PRDIII-I region of human interferon-B promoter strand 1polymer3210069.51
2B
(F)
PRDIII-I region of human interferon-B promoter strand 2polymer329610.21
3C, D, E, F
(A, B, C, D)
Interferon regulatory factor 3polymer11613398.14UniProt (Q14653)
Pfam (PF00605)
Homo sapiens (human)IRF-3
4G, H, I, J, K...
(E, F, A, B, C...)
waterwater18.0123Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 113 (UniProt: Q14653)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight73272.2
All*Total formula weight73272.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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