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9QOO

Composite model: Ternary complex of the human 20S proteasome in complex with Importin-9 and two homodimers of Akirin-2

Summary for 9QOO
Entry DOI10.2210/pdb9qoo/pdb
Related9QNO 9QON
EMDB information53265
DescriptorImportin-9, Akirin-2, Proteasome subunit alpha type-3, ... (9 entities in total)
Functional Keywords20s proteasome, 20s, proteasome, nuclear iport, akirin, akirin2, importin 9, importin, protein transport
Biological sourceHomo sapiens (human)
More
Total number of polymer chains12
Total formula weight401481.23
Authors
Brunner, H.L.,Grundmann, L.,David, H. (deposition date: 2025-03-26, release date: 2026-01-28)
Primary citationBrunner, H.,Kalis, R.W.,Grundmann, L.,Hodakova, Z.,Koskova, Z.,Grishkovskaya, I.,de Almeida, M.,Hinterndorfer, M.,Hoefflin, S.,Andersch, F.,Kotisch, H.,Dickmanns, A.,Cuylen-Haering, S.,Zuber, J.,Haselbach, D.
A multivalent adaptor mechanism drives the nuclear import of proteasomes
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

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PDB entries from 2026-01-28

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