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9QON

Ternary complex of the human 20S proteasome in complex with Importin-9 and two homodimers of Akirin-2 - focussed refinement on the alpha subunits, Ipo-9 and Ak2

Summary for 9QON
Entry DOI10.2210/pdb9qon/pdb
EMDB information53264
DescriptorImportin-9, Akirin-2, Proteasome subunit alpha type-3, ... (9 entities in total)
Functional Keywords20s proteasome, 20s, proteasome, nuclear iport, akirin, akirin2, importin 9, importin, protein transport
Biological sourceHomo sapiens (human)
More
Total number of polymer chains11
Total formula weight378955.65
Authors
Brunner, H.L.,Grundmann, L.,David, H. (deposition date: 2025-03-26, release date: 2026-01-28)
Primary citationBrunner, H.,Kalis, R.W.,Grundmann, L.,Hodakova, Z.,Koskova, Z.,Grishkovskaya, I.,de Almeida, M.,Hinterndorfer, M.,Hoefflin, S.,Andersch, F.,Kotisch, H.,Dickmanns, A.,Cuylen-Haering, S.,Zuber, J.,Haselbach, D.
A multivalent adaptor mechanism drives the nuclear import of proteasomes
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation

248335

PDB entries from 2026-01-28

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