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9QOO

Composite model: Ternary complex of the human 20S proteasome in complex with Importin-9 and two homodimers of Akirin-2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Importin-9polymer1041116062.31UniProt (Q96P70)Homo sapiens (human)Imp9,Ran-binding protein 9,RanBP9
2B, C, D, G
(B, C, D, I)
Akirin-2polymer20322525.64UniProt (Q53H80)Homo sapiens (human)
3E
(F)
Proteasome subunit alpha type-3polymer25528469.31UniProt (P25788)Homo sapiens (human)Macropain subunit C8,Multicatalytic endopeptidase complex subunit C8,Proteasome component C8
4F
(G)
Proteasome subunit alpha type-6polymer24627432.51UniProt (P60900)Homo sapiens (human)27 kDa prosomal protein,p27K,Macropain iota chain,Multicatalytic endopeptidase complex iota chain,Proteasome iota chain
5H
(O)
Proteasome subunit alpha type-2polymer23425927.51UniProt (P25787)Homo sapiens (human)Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3
6I
(P)
Proteasome subunit alpha type-4polymer26129525.81UniProt (P25789)Homo sapiens (human)Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L
7J
(Q)
Proteasome subunit alpha type-7polymer24827929.91UniProt (O14818)Homo sapiens (human)Proteasome subunit RC6-1,Proteasome subunit XAPC7
8K
(R)
Proteasome subunit alpha type-5polymer24126436.01UniProt (P28066)Homo sapiens (human)Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome zeta chain
9L
(S)
Proteasome subunit alpha type-1polymer26329595.61UniProt (P25786)Homo sapiens (human)30 kDa prosomal protein,PROS-30,Macropain subunit C2,Multicatalytic endopeptidase complex subunit C2,Proteasome component C2,Proteasome nu chain
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight401481.2
All*Total formula weight401481.2
*Water molecules are not included.

248335

PDB entries from 2026-01-28

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