9QOO

Composite model: Ternary complex of the human 20S proteasome in complex with Importin-9 and two homodimers of Akirin-2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006606	biological_process	protein import into nucleus
A	0016020	cellular_component	membrane
A	0031144	biological_process	proteasome localization
A	0042393	molecular_function	histone binding
A	0061608	molecular_function	nuclear import signal receptor activity
A	0140713	molecular_function	histone chaperone activity
B	0000785	cellular_component	chromatin
B	0002821	biological_process	positive regulation of adaptive immune response
B	0003712	molecular_function	transcription coregulator activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0006606	biological_process	protein import into nucleus
B	0009792	biological_process	embryo development ending in birth or egg hatching
B	0016020	cellular_component	membrane
B	0017053	cellular_component	transcription repressor complex
B	0019899	molecular_function	enzyme binding
B	0021987	biological_process	cerebral cortex development
B	0030674	molecular_function	protein-macromolecule adaptor activity
B	0031144	biological_process	proteasome localization
B	0032755	biological_process	positive regulation of interleukin-6 production
B	0042742	biological_process	defense response to bacterium
B	0042802	molecular_function	identical protein binding
B	0045089	biological_process	positive regulation of innate immune response
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0050871	biological_process	positive regulation of B cell activation
B	0051147	biological_process	regulation of muscle cell differentiation
B	0071630	biological_process	nuclear protein quality control by the ubiquitin-proteasome system
C	0000785	cellular_component	chromatin
C	0002821	biological_process	positive regulation of adaptive immune response
C	0003712	molecular_function	transcription coregulator activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0006606	biological_process	protein import into nucleus
C	0009792	biological_process	embryo development ending in birth or egg hatching
C	0016020	cellular_component	membrane
C	0017053	cellular_component	transcription repressor complex
C	0019899	molecular_function	enzyme binding
C	0021987	biological_process	cerebral cortex development
C	0030674	molecular_function	protein-macromolecule adaptor activity
C	0031144	biological_process	proteasome localization
C	0032755	biological_process	positive regulation of interleukin-6 production
C	0042742	biological_process	defense response to bacterium
C	0042802	molecular_function	identical protein binding
C	0045089	biological_process	positive regulation of innate immune response
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	0050871	biological_process	positive regulation of B cell activation
C	0051147	biological_process	regulation of muscle cell differentiation
C	0071630	biological_process	nuclear protein quality control by the ubiquitin-proteasome system
D	0000785	cellular_component	chromatin
D	0002821	biological_process	positive regulation of adaptive immune response
D	0003712	molecular_function	transcription coregulator activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0006606	biological_process	protein import into nucleus
D	0009792	biological_process	embryo development ending in birth or egg hatching
D	0016020	cellular_component	membrane
D	0017053	cellular_component	transcription repressor complex
D	0019899	molecular_function	enzyme binding
D	0021987	biological_process	cerebral cortex development
D	0030674	molecular_function	protein-macromolecule adaptor activity
D	0031144	biological_process	proteasome localization
D	0032755	biological_process	positive regulation of interleukin-6 production
D	0042742	biological_process	defense response to bacterium
D	0042802	molecular_function	identical protein binding
D	0045089	biological_process	positive regulation of innate immune response
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0050871	biological_process	positive regulation of B cell activation
D	0051147	biological_process	regulation of muscle cell differentiation
D	0071630	biological_process	nuclear protein quality control by the ubiquitin-proteasome system
F	0000502	cellular_component	proteasome complex
F	0002376	biological_process	immune system process
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005839	cellular_component	proteasome core complex
F	0006281	biological_process	DNA repair
F	0006915	biological_process	apoptotic process
F	0006974	biological_process	DNA damage response
F	0006979	biological_process	response to oxidative stress
F	0007283	biological_process	spermatogenesis
F	0008021	cellular_component	synaptic vesicle
F	0010498	biological_process	proteasomal protein catabolic process
F	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
F	0019773	cellular_component	proteasome core complex, alpha-subunit complex
F	0030317	biological_process	flagellated sperm motility
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0032729	biological_process	positive regulation of type II interferon production
F	0032743	biological_process	positive regulation of interleukin-2 production
F	0032760	biological_process	positive regulation of tumor necrosis factor production
F	0034341	biological_process	response to type II interferon
F	0034515	cellular_component	proteasome storage granule
F	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
F	0045061	biological_process	thymic T cell selection
F	0045063	biological_process	T-helper 1 cell differentiation
F	0045590	biological_process	negative regulation of regulatory T cell differentiation
F	0051321	biological_process	meiotic cell cycle
F	0061136	biological_process	regulation of proteasomal protein catabolic process
F	0070062	cellular_component	extracellular exosome
F	0071357	biological_process	cellular response to type I interferon
F	0072539	biological_process	T-helper 17 cell differentiation
F	0140756	molecular_function	structural constituent of proteasome
F	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
F	1990111	cellular_component	spermatoproteasome complex
F	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
G	0000502	cellular_component	proteasome complex
G	0000932	cellular_component	P-body
G	0002376	biological_process	immune system process
G	0003723	molecular_function	RNA binding
G	0004175	molecular_function	endopeptidase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005839	cellular_component	proteasome core complex
G	0005840	cellular_component	ribosome
G	0006281	biological_process	DNA repair
G	0006915	biological_process	apoptotic process
G	0006974	biological_process	DNA damage response
G	0006979	biological_process	response to oxidative stress
G	0007283	biological_process	spermatogenesis
G	0008021	cellular_component	synaptic vesicle
G	0010498	biological_process	proteasomal protein catabolic process
G	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
G	0016363	cellular_component	nuclear matrix
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0030016	cellular_component	myofibril
G	0030017	cellular_component	sarcomere
G	0030163	biological_process	protein catabolic process
G	0030317	biological_process	flagellated sperm motility
G	0032729	biological_process	positive regulation of type II interferon production
G	0032743	biological_process	positive regulation of interleukin-2 production
G	0032760	biological_process	positive regulation of tumor necrosis factor production
G	0034341	biological_process	response to type II interferon
G	0034515	cellular_component	proteasome storage granule
G	0035639	molecular_function	purine ribonucleoside triphosphate binding
G	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
G	0045061	biological_process	thymic T cell selection
G	0045063	biological_process	T-helper 1 cell differentiation
G	0045590	biological_process	negative regulation of regulatory T cell differentiation
G	0050727	biological_process	regulation of inflammatory response
G	0051059	molecular_function	NF-kappaB binding
G	0051321	biological_process	meiotic cell cycle
G	0061136	biological_process	regulation of proteasomal protein catabolic process
G	0070062	cellular_component	extracellular exosome
G	0071357	biological_process	cellular response to type I interferon
G	0072539	biological_process	T-helper 17 cell differentiation
G	0097229	cellular_component	sperm end piece
G	0097542	cellular_component	ciliary tip
G	0140756	molecular_function	structural constituent of proteasome
G	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
G	1990111	cellular_component	spermatoproteasome complex
G	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
I	0000785	cellular_component	chromatin
I	0002821	biological_process	positive regulation of adaptive immune response
I	0003712	molecular_function	transcription coregulator activity
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0006606	biological_process	protein import into nucleus
I	0009792	biological_process	embryo development ending in birth or egg hatching
I	0016020	cellular_component	membrane
I	0017053	cellular_component	transcription repressor complex
I	0019899	molecular_function	enzyme binding
I	0021987	biological_process	cerebral cortex development
I	0030674	molecular_function	protein-macromolecule adaptor activity
I	0031144	biological_process	proteasome localization
I	0032755	biological_process	positive regulation of interleukin-6 production
I	0042742	biological_process	defense response to bacterium
I	0042802	molecular_function	identical protein binding
I	0045089	biological_process	positive regulation of innate immune response
I	0045944	biological_process	positive regulation of transcription by RNA polymerase II
I	0050871	biological_process	positive regulation of B cell activation
I	0051147	biological_process	regulation of muscle cell differentiation
I	0071630	biological_process	nuclear protein quality control by the ubiquitin-proteasome system
O	0000502	cellular_component	proteasome complex
O	0000932	cellular_component	P-body
O	0002376	biological_process	immune system process
O	0005515	molecular_function	protein binding
O	0005576	cellular_component	extracellular region
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005839	cellular_component	proteasome core complex
O	0006281	biological_process	DNA repair
O	0006915	biological_process	apoptotic process
O	0006974	biological_process	DNA damage response
O	0006979	biological_process	response to oxidative stress
O	0007283	biological_process	spermatogenesis
O	0008021	cellular_component	synaptic vesicle
O	0009615	biological_process	response to virus
O	0010498	biological_process	proteasomal protein catabolic process
O	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
O	0019773	cellular_component	proteasome core complex, alpha-subunit complex
O	0030317	biological_process	flagellated sperm motility
O	0032729	biological_process	positive regulation of type II interferon production
O	0032743	biological_process	positive regulation of interleukin-2 production
O	0032760	biological_process	positive regulation of tumor necrosis factor production
O	0034341	biological_process	response to type II interferon
O	0034515	cellular_component	proteasome storage granule
O	0034774	cellular_component	secretory granule lumen
O	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
O	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
O	0045061	biological_process	thymic T cell selection
O	0045063	biological_process	T-helper 1 cell differentiation
O	0045590	biological_process	negative regulation of regulatory T cell differentiation
O	0051321	biological_process	meiotic cell cycle
O	0061136	biological_process	regulation of proteasomal protein catabolic process
O	0070062	cellular_component	extracellular exosome
O	0071357	biological_process	cellular response to type I interferon
O	0072539	biological_process	T-helper 17 cell differentiation
O	0140756	molecular_function	structural constituent of proteasome
O	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
O	1904813	cellular_component	ficolin-1-rich granule lumen
O	1990111	cellular_component	spermatoproteasome complex
O	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
P	0000502	cellular_component	proteasome complex
P	0000932	cellular_component	P-body
P	0002376	biological_process	immune system process
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005839	cellular_component	proteasome core complex
P	0006281	biological_process	DNA repair
P	0006915	biological_process	apoptotic process
P	0006974	biological_process	DNA damage response
P	0006979	biological_process	response to oxidative stress
P	0007283	biological_process	spermatogenesis
P	0008021	cellular_component	synaptic vesicle
P	0010498	biological_process	proteasomal protein catabolic process
P	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
P	0019773	cellular_component	proteasome core complex, alpha-subunit complex
P	0030317	biological_process	flagellated sperm motility
P	0032729	biological_process	positive regulation of type II interferon production
P	0032743	biological_process	positive regulation of interleukin-2 production
P	0032760	biological_process	positive regulation of tumor necrosis factor production
P	0034341	biological_process	response to type II interferon
P	0034515	cellular_component	proteasome storage granule
P	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
P	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
P	0045061	biological_process	thymic T cell selection
P	0045063	biological_process	T-helper 1 cell differentiation
P	0045590	biological_process	negative regulation of regulatory T cell differentiation
P	0051321	biological_process	meiotic cell cycle
P	0061136	biological_process	regulation of proteasomal protein catabolic process
P	0070062	cellular_component	extracellular exosome
P	0071357	biological_process	cellular response to type I interferon
P	0072539	biological_process	T-helper 17 cell differentiation
P	0140756	molecular_function	structural constituent of proteasome
P	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
P	1990111	cellular_component	spermatoproteasome complex
P	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
Q	0000502	cellular_component	proteasome complex
Q	0002376	biological_process	immune system process
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005839	cellular_component	proteasome core complex
Q	0006281	biological_process	DNA repair
Q	0006915	biological_process	apoptotic process
Q	0006974	biological_process	DNA damage response
Q	0006979	biological_process	response to oxidative stress
Q	0008021	cellular_component	synaptic vesicle
Q	0010498	biological_process	proteasomal protein catabolic process
Q	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
Q	0019773	cellular_component	proteasome core complex, alpha-subunit complex
Q	0030317	biological_process	flagellated sperm motility
Q	0032729	biological_process	positive regulation of type II interferon production
Q	0032743	biological_process	positive regulation of interleukin-2 production
Q	0032760	biological_process	positive regulation of tumor necrosis factor production
Q	0034341	biological_process	response to type II interferon
Q	0034515	cellular_component	proteasome storage granule
Q	0042802	molecular_function	identical protein binding
Q	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Q	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
Q	0045061	biological_process	thymic T cell selection
Q	0045063	biological_process	T-helper 1 cell differentiation
Q	0045590	biological_process	negative regulation of regulatory T cell differentiation
Q	0061136	biological_process	regulation of proteasomal protein catabolic process
Q	0070062	cellular_component	extracellular exosome
Q	0071357	biological_process	cellular response to type I interferon
Q	0072539	biological_process	T-helper 17 cell differentiation
Q	0140756	molecular_function	structural constituent of proteasome
Q	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
Q	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
R	0000502	cellular_component	proteasome complex
R	0002376	biological_process	immune system process
R	0005515	molecular_function	protein binding
R	0005576	cellular_component	extracellular region
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005839	cellular_component	proteasome core complex
R	0006281	biological_process	DNA repair
R	0006915	biological_process	apoptotic process
R	0006974	biological_process	DNA damage response
R	0006979	biological_process	response to oxidative stress
R	0007283	biological_process	spermatogenesis
R	0008021	cellular_component	synaptic vesicle
R	0010498	biological_process	proteasomal protein catabolic process
R	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
R	0019773	cellular_component	proteasome core complex, alpha-subunit complex
R	0030317	biological_process	flagellated sperm motility
R	0032729	biological_process	positive regulation of type II interferon production
R	0032743	biological_process	positive regulation of interleukin-2 production
R	0032760	biological_process	positive regulation of tumor necrosis factor production
R	0034341	biological_process	response to type II interferon
R	0034515	cellular_component	proteasome storage granule
R	0034774	cellular_component	secretory granule lumen
R	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
R	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
R	0045061	biological_process	thymic T cell selection
R	0045063	biological_process	T-helper 1 cell differentiation
R	0045590	biological_process	negative regulation of regulatory T cell differentiation
R	0051321	biological_process	meiotic cell cycle
R	0061136	biological_process	regulation of proteasomal protein catabolic process
R	0070062	cellular_component	extracellular exosome
R	0071357	biological_process	cellular response to type I interferon
R	0072539	biological_process	T-helper 17 cell differentiation
R	0140756	molecular_function	structural constituent of proteasome
R	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
R	1904813	cellular_component	ficolin-1-rich granule lumen
R	1990111	cellular_component	spermatoproteasome complex
R	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
S	0000502	cellular_component	proteasome complex
S	0001530	molecular_function	lipopolysaccharide binding
S	0002376	biological_process	immune system process
S	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005839	cellular_component	proteasome core complex
S	0006281	biological_process	DNA repair
S	0006915	biological_process	apoptotic process
S	0006974	biological_process	DNA damage response
S	0006979	biological_process	response to oxidative stress
S	0007283	biological_process	spermatogenesis
S	0008021	cellular_component	synaptic vesicle
S	0010498	biological_process	proteasomal protein catabolic process
S	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
S	0016604	cellular_component	nuclear body
S	0019773	cellular_component	proteasome core complex, alpha-subunit complex
S	0030317	biological_process	flagellated sperm motility
S	0032729	biological_process	positive regulation of type II interferon production
S	0032743	biological_process	positive regulation of interleukin-2 production
S	0032760	biological_process	positive regulation of tumor necrosis factor production
S	0034341	biological_process	response to type II interferon
S	0034515	cellular_component	proteasome storage granule
S	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
S	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
S	0045061	biological_process	thymic T cell selection
S	0045063	biological_process	T-helper 1 cell differentiation
S	0045590	biological_process	negative regulation of regulatory T cell differentiation
S	0051321	biological_process	meiotic cell cycle
S	0061136	biological_process	regulation of proteasomal protein catabolic process
S	0070062	cellular_component	extracellular exosome
S	0071357	biological_process	cellular response to type I interferon
S	0072539	biological_process	T-helper 17 cell differentiation
S	0140756	molecular_function	structural constituent of proteasome
S	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
S	1990111	cellular_component	spermatoproteasome complex
S	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle

Functional Information from PROSITE/UniProt

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdraiTvFSPdGHlfQVEYAqeA

Chain	Residue	Details
Q	TYR3-ALA25
R	TYR8-ALA30
F	TYR7-ALA29
O	TYR5-ALA27
G	PHE9-ALA31
P	TYR5-ALA27
S	TYR6-ALA28

---

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. LGIlAndGVLLAAErrnihklldevffse.KiyklnedmacsvaGitSD

Chain	Residue	Details
P	LEU35-ASP82

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	76
Details	Domain: {"description":"Importin N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00115","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Motif: {"description":"SYVS motif","evidences":[{"source":"PubMed","id":"34711951","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9QUM9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P49722","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P17220","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1 and ABL2","evidences":[{"source":"PubMed","id":"16678104","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"UniProtKB","id":"Q9Z2U1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; alternate","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine; alternate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}

Chain

Residue

Details

---