9C1W

Structure of AKT2 with compound 3

Summary for 9C1W

• Entry DOI: 10.2210/pdb9c1w/pdb
• Related: 8UVY 8UW2 8UW7 8UW9
• Descriptor: RAC-beta serine/threonine-protein kinase, 4-{2-[({4-[(2P)-2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: inhibitor, kinase, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 52662.13

Authors

Craven, G.B.,Ma, X.,Taunton, J. (deposition date: 2024-05-29, release date: 2024-09-04)

• Primary citation: Craven, G.B.,Ma, X.,Taunton, J.; Mutant-selective AKT1 inhibitors via lysine targeting and neo-zinc chelation; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)