9C1W
Structure of AKT2 with compound 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RAC-beta serine/threonine-protein kinase | polymer | 446 | 51749.1 | 1 | UniProt (P31751) Pfam (PF00169) Pfam (PF00069) Pfam (PF00433) | Homo sapiens (human) | Protein kinase Akt-2,Protein kinase B beta,PKB beta,RAC protein kinase beta,RAC-PK-beta |
| 2 | B (A) | 4-{2-[({4-[(2P)-2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | non-polymer | 540.6 | 1 | Chemie (XOO) | |||
| 3 | C, D, E, F, G... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | I (A) | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A: 2 - 447 (UniProt: P31751)
| PDB | External Database | Details |
|---|---|---|
| Ala 115 | Pro 115 | engineered mutation |
| Ala 116 | Gly 116 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51749.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 913.0 | |
| All* | Total formula weight | 52662.1 |
