Summary for 8V9C
| Entry DOI | 10.2210/pdb8v9c/pdb |
| Related | 5HOT 8USY 8V0Z |
| Descriptor | Integrase, (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid (2 entities in total) |
| Functional Keywords | hiv-1, viral protein, hiv-1 integrase, allosteric inhibitor, allini, viral protein-inhibitor complex, viral protein/inhibitor |
| Biological source | Human immunodeficiency virus 1 |
| Total number of polymer chains | 2 |
| Total formula weight | 66395.65 |
| Authors | Montermoso, S.,Gupta, K.,Eilers, G.,Bushman, F.D.,Van Duyne, G.D. (deposition date: 2023-12-07, release date: 2025-03-19, Last modification date: 2025-03-26) |
| Primary citation | Montermoso, S.,Gupta, K.,Eilers, G.,Allen, A.,Stewart, N.,Gore, A.,An, N.,Hwang, Y.,Sharp, R.,Bushman, F.D.,Van Duyne, G.D. Structural Consequences of Resistance Mutations on the Formation of ALLINI-Induced Branched Polymers of HIV-1 Integrase To Be Published, |
| Experimental method | X-RAY DIFFRACTION (4.4 Å) |
Structure validation
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