8SIH

Crystal Structure of PRMT4 with Compound YD1-289

Summary for 8SIH

• Entry DOI: 10.2210/pdb8sih/pdb
• Descriptor: Histone-arginine methyltransferase CARM1, 5'-{[2-(benzylcarbamamido)ethyl][3-(N'-cyclopentylcarbamimidamido)propyl]amino}-5'-deoxyadenosine, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: prmt4, yd1-289, transferase, structural genomics, psi-2, protein structure initiative, structural genomics consortium, sgc, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 41636.40

Authors

Song, X.,Dong, A.,Deng, Y.,Huang, R.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2023-04-16, release date: 2024-04-24)

• Primary citation: Song, X.,Dong, A.,Deng, Y.,Huang, R.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC); Crystal Structure of PRMT4 with Compound YD1-289; To be published,

Experimental method

X-RAY DIFFRACTION (2.35 Å)