8SIH

Crystal Structure of PRMT4 with Compound YD1-289

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016274	molecular_function	protein-arginine N-methyltransferase activity
A	0018216	biological_process	peptidyl-arginine methylation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000305|PubMed:21410432

Chain	Residue	Details
A	GLN159
A	ARG168
A	GLY192
A	GLU214
A	GLU243
A	SER271

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:19843527

Chain	Residue	Details
A	SER216

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:34480022

Chain	Residue	Details
A	LYS227

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