8IO3

Cryo-EM structure of human HCN3 channel with cilobradine

Summary for 8IO3

• Entry DOI: 10.2210/pdb8io3/pdb
• EMDB information: 35606
• Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3, 3-[[(3~{S})-1-[2-(3,4-dimethoxyphenyl)ethyl]piperidin-3-yl]methyl]-7,8-dimethoxy-2,5-dihydro-1~{H}-3-benzazepin-4-one (2 entities in total)
• Functional Keywords: human hcn3 channel, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 346502.14

Authors

Yu, B.,Lu, Q.Y.,Li, J.,Zhang, J. (deposition date: 2023-03-10, release date: 2024-04-10)

• Primary citation: Yu, B.,Lu, Q.Y.,Li, J.,Zhang, J.; Cryo-EM structure of human HCN3 channel with cilobradine; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.02 Å)