8HCH
Crystal structure of mTREX1-Uridine complex
Summary for 8HCH
Entry DOI | 10.2210/pdb8hch/pdb |
Related | 8HCC 8HCD 8HCE 8HCF 8HCG |
Descriptor | Three-prime repair exonuclease 1, MAGNESIUM ION, URIDINE, ... (4 entities in total) |
Functional Keywords | trex1, deddh exonuclease, dnase, rnase, uridine, hydrolase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 4 |
Total formula weight | 110862.64 |
Authors | Hsiao, Y.Y.,Huang, K.W.,Wu, C.Y. (deposition date: 2022-11-01, release date: 2023-11-08, Last modification date: 2023-12-13) |
Primary citation | Huang, K.W.,Wu, C.Y.,Toh, S.I.,Liu, T.C.,Tu, C.I.,Lin, Y.H.,Cheng, A.J.,Kao, Y.T.,Chu, J.W.,Hsiao, Y.Y. Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51:11927-11940, 2023 Cited by PubMed: 37870446DOI: 10.1093/nar/gkad910 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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