8EQS

Structure of SARS-CoV-1 Orf3a in late endosome/lysosome-like environment, MSP1D1 nanodisc

Summary for 8EQS

Entry DOI	10.2210/pdb8eqs/pdb
EMDB information	28544
Descriptor	ORF3a protein, Apolipoprotein A-I, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (3 entities in total)
Functional Keywords	membrane protein, sars-cov, sars-cov-2, viral protein
Biological source	Severe acute respiratory syndrome coronavirus (SARS-CoV) More
Total number of polymer chains	4
Total formula weight	123433.96
Authors	Miller, A.N.,Houlihan, P.R.,Matamala, E.,Cabezas-Bratesco, D.,Lee, G.Y.,Cristofori-Armstrong, B.,Dilan, T.L.,Sanchez-Martinez, S.,Matthies, D.,Yan, R.,Yu, Z.,Ren, D.,Brauchi, S.E.,Clapham, D.E. (deposition date: 2022-10-09, release date: 2023-02-08)
Primary citation	Miller, A.N.,Houlihan, P.R.,Matamala, E.,Cabezas-Bratesco, D.,Lee, G.Y.,Cristofori-Armstrong, B.,Dilan, T.L.,Sanchez-Martinez, S.,Matthies, D.,Yan, R.,Yu, Z.,Ren, D.,Brauchi, S.E.,Clapham, D.E. The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins. Elife, 12:-, 2023 Cited by PubMed: 36695574 DOI: 10.7554/eLife.84477 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation