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6N27
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BU of 6n27 by Molmil
BEST1 calcium-bound closed state
Descriptor: Bestrophin homolog, CALCIUM ION
Authors:Miller, A.N, Vaisey, G, Long, S.B.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin.
Elife, 8, 2019
6N24
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BU of 6n24 by Molmil
BEST1 open state W287F mutant, calcium-free
Descriptor: Bestrophin homolog
Authors:Miller, A.N, Vaisey, G, Long, S.B.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin.
Elife, 8, 2019
6N26
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BU of 6n26 by Molmil
BEST1 calcium-free closed state
Descriptor: Bestrophin homolog
Authors:Miller, A.N, Vaisey, G, Long, S.B.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin.
Elife, 8, 2019
6N23
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BU of 6n23 by Molmil
BEST1 in a calcium-bound inactivated state
Descriptor: Bestrophin homolog, CALCIUM ION
Authors:Miller, A.N, Vaisey, G, Long, S.B.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin.
Elife, 8, 2019
6N28
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BU of 6n28 by Molmil
BEST1 calcium-bound open state
Descriptor: Bestrophin homolog, CALCIUM ION
Authors:Miller, A.N, Vaisey, G, Long, S.B.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin.
Elife, 8, 2019
8EQS
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BU of 8eqs by Molmil
Structure of SARS-CoV-1 Orf3a in late endosome/lysosome-like environment, MSP1D1 nanodisc
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Apolipoprotein A-I, ORF3a protein
Authors:Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
Deposit date:2022-10-09
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
8EQJ
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BU of 8eqj by Molmil
Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like membrane environment, MSP1D1 nanodisc
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein
Authors:Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
Deposit date:2022-10-07
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
8EQT
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BU of 8eqt by Molmil
Structure of SARS-CoV-2 Orf3a in plasma membrane-like environment, MSP1D1 nanodisc
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein
Authors:Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
Deposit date:2022-10-09
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
8EQU
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BU of 8equ by Molmil
Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like environment, Saposin A nanodisc
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein, Saposin A, ...
Authors:Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
Deposit date:2022-10-09
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
6N25
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BU of 6n25 by Molmil
BEST1 open state W287F mutant, calcium-bound
Descriptor: Bestrophin homolog, CALCIUM ION
Authors:Miller, A.N, Vaisey, G, Long, S.B.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin.
Elife, 8, 2019
3UKM
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BU of 3ukm by Molmil
Crystal structure of the human two pore domain potassium ion channel K2P1 (TWIK-1)
Descriptor: POTASSIUM ION, Potassium channel subfamily K member 1, UNDECANE
Authors:Long, S.B, Miller, A.N.
Deposit date:2011-11-09
Release date:2012-02-08
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of the human two-pore domain potassium channel K2P1.
Science, 335, 2012
5T5N
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BU of 5t5n by Molmil
Calcium-activated chloride channel bestrophin-1 (BEST1), triple mutant: I76A, F80A, F84A; in complex with an Fab antibody fragment, chloride, and calcium
Descriptor: CALCIUM ION, CHLORIDE ION, Fab antibody fragment, ...
Authors:Long, S.B, Vaisey, G.
Deposit date:2016-08-31
Release date:2016-11-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Distinct regions that control ion selectivity and calcium-dependent activation in the bestrophin ion channel.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016

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