8D5B
Crystal structure of human METTL1 in complex with SAH
Summary for 8D5B
Entry DOI | 10.2210/pdb8d5b/pdb |
Descriptor | tRNA (guanine-N(7)-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... (7 entities in total) |
Functional Keywords | cancer protein, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 31345.88 |
Authors | |
Primary citation | Ruiz-Arroyo, V.M.,Raj, R.,Babu, K.,Onolbaatar, O.,Roberts, P.H.,Nam, Y. Structures and mechanisms of tRNA methylation by METTL1-WDR4. Nature, 613:383-390, 2023 Cited by PubMed: 36599982DOI: 10.1038/s41586-022-05565-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
Download full validation report