8BP2

2.8A STRUCTURE OF ZOLIFLODACIN WITH S.AUREUS DNA GYRASE AND DNA

This is a non-PDB format compatible entry.

Summary for 8BP2

• Entry DOI: 10.2210/pdb8bp2/pdb
• Related: 5CDM 5CDO
• Descriptor: DNA gyrase subunit B, DNA gyrase subunit A, DNA (20-MER), ... (9 entities in total)
• Functional Keywords: type iia topoisomerase, antibacterial, inhibitor, isomerase
• Biological source: Staphylococcus aureus; More
• Total number of polymer chains: 8
• Total formula weight: 180243.45

Authors

Bax, B.D.,Morgan, H.,Warren, A.J. (deposition date: 2022-11-15, release date: 2023-02-08, Last modification date: 2024-02-07)

• Primary citation: Morgan, H.,Lipka-Lloyd, M.,Warren, A.J.,Hughes, N.,Holmes, J.,Burton, N.P.,Mahenthiralingam, E.,Bax, B.D.; A 2.8 angstrom Structure of Zoliflodacin in a DNA Cleavage Complex with Staphylococcus aureus DNA Gyrase.; Int J Mol Sci, 24:-, 2023; PubMed: 36675148; DOI: 10.3390/ijms24021634

Experimental method

X-RAY DIFFRACTION (2.8 Å)