8BP2

2.8A STRUCTURE OF ZOLIFLODACIN WITH S.AUREUS DNA GYRASE AND DNA

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0003677	molecular_function	DNA binding
AAA	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
AAA	0005524	molecular_function	ATP binding
AAA	0006259	biological_process	DNA metabolic process
AAA	0006265	biological_process	DNA topological change
BBB	0003677	molecular_function	DNA binding
BBB	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
BBB	0005524	molecular_function	ATP binding
BBB	0006265	biological_process	DNA topological change
CCC	0003677	molecular_function	DNA binding
CCC	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
CCC	0005524	molecular_function	ATP binding
CCC	0006259	biological_process	DNA metabolic process
CCC	0006265	biological_process	DNA topological change
DDD	0003677	molecular_function	DNA binding
DDD	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
DDD	0005524	molecular_function	ATP binding
DDD	0006265	biological_process	DNA topological change

Functional Information from PROSITE/UniProt

site_id	PS00177
Number of Residues	9
Details	TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG

Chain	Residue	Details
BBB	LEU433-GLY441

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	228
Details	Domain: {"description":"Toprim","evidences":[{"source":"HAMAP-Rule","id":"MF_01898","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01898","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Interaction with DNA","evidences":[{"source":"HAMAP-Rule","id":"MF_01898","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Active site: {"description":"O-(5'-phospho-DNA)-tyrosine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_01897","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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