7USE

Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site

7USE の概要

• エントリーDOI: 10.2210/pdb7use/pdb
• EMDBエントリー: 26734
• 分子名称: Cytoplasmic FMR1-interacting protein 1, GUANOSINE-5'-TRIPHOSPHATE, Nck-associated protein 1, ... (10 entities in total)
• 機能のキーワード: actin regulator, gtpase binding protein, cytoskeletal regulator, cell invasion
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 381242.21

構造登録者

Ding, B.,Yang, S.,Chen, B.,Chowdhury, S. (登録日: 2022-04-25, 公開日: 2022-09-21, 最終更新日: 2024-06-12)

• 主引用文献: Ding, B.,Yang, S.,Schaks, M.,Liu, Y.,Brown, A.J.,Rottner, K.,Chowdhury, S.,Chen, B.; Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.; Nat Commun, 13:5444-5444, 2022; PubMed: 36114192; DOI: 10.1038/s41467-022-33174-3

実験手法

ELECTRON MICROSCOPY (3 Å)