7S6B
Crystal structure of modular polyketide synthase apo-Lsd14 from the Lasalocid biosynthesis pathway, trapped in the transacylation step
Summary for 7S6B
Entry DOI | 10.2210/pdb7s6b/pdb |
Descriptor | Polyketide synthase, ... (4 entities in total) |
Functional Keywords | modular polyketide synthase, ketosynthase, acyltransferase, acyl carrier protein, biosynthetic protein |
Biological source | Streptomyces lasalocidi More |
Total number of polymer chains | 5 |
Total formula weight | 332236.98 |
Authors | Bagde, S.R.,Mathews, I.I.,Kim, C.-Y. (deposition date: 2021-09-13, release date: 2021-11-03, Last modification date: 2024-05-22) |
Primary citation | Bagde, S.R.,Mathews, I.I.,Fromme, J.C.,Kim, C.Y. Modular polyketide synthase contains two reaction chambers that operate asynchronously. Science, 374:723-729, 2021 Cited by PubMed: 34735234DOI: 10.1126/science.abi8532 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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