7S6B

Crystal structure of modular polyketide synthase apo-Lsd14 from the Lasalocid biosynthesis pathway, trapped in the transacylation step

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Polyketide synthase	polymer	944	100185.0	2	UniProt (B6ZK67) Pfam (PF08990) Pfam (PF00109) Pfam (PF02801) Pfam (PF16197) Pfam (PF00698) In PDB	Streptomyces lasalocidi
2	C, D	Polyketide synthase	polymer	544	56170.6	2	UniProt (B6ZK67) Pfam (PF18369) Pfam (PF08659) In PDB	Streptomyces lasalocidi
3	E	Polyketide synthase	polymer	179	19525.8	1	UniProt (B6ZK67) Pfam (PF00550) In PDB	Streptomyces lasalocidi
4		water	water		18.0	829	Chemie (HOH)

Sequence modifications

A, B: 1 - 924 (UniProt: B6ZK67)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	332237.0
All*	Total formula weight	332237.0

*Water molecules are not included.