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7S6B

Crystal structure of modular polyketide synthase apo-Lsd14 from the Lasalocid biosynthesis pathway, trapped in the transacylation step

Functional Information from GO Data
ChainGOidnamespacecontents
A0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
A0006633biological_processfatty acid biosynthetic process
A0016740molecular_functiontransferase activity
A0016746molecular_functionacyltransferase activity
B0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
B0006633biological_processfatty acid biosynthetic process
B0016740molecular_functiontransferase activity
B0016746molecular_functionacyltransferase activity
E0031177molecular_functionphosphopantetheine binding
Functional Information from PROSITE/UniProt
site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGFDSLMAVELRNRI
ChainResidueDetails
EASP1521-ILE1536

site_idPS00606
Number of Residues17
DetailsKS3_1 Ketosynthase family 3 (KS3) active site signature. GPAvtIDtACSSSlvAL
ChainResidueDetails
AGLY201-LEU217

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PDB entries from 2024-09-11

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