7S6B

Crystal structure of modular polyketide synthase apo-Lsd14 from the Lasalocid biosynthesis pathway, trapped in the transacylation step

Summary for 7S6B

Entry DOI	10.2210/pdb7s6b/pdb
Descriptor	Polyketide synthase, ... (4 entities in total)
Functional Keywords	modular polyketide synthase, ketosynthase, acyltransferase, acyl carrier protein, biosynthetic protein
Biological source	Streptomyces lasalocidi More
Total number of polymer chains	5
Total formula weight	332236.98
Authors	Bagde, S.R.,Mathews, I.I.,Kim, C.-Y. (deposition date: 2021-09-13, release date: 2021-11-03, Last modification date: 2024-05-22)
Primary citation	Bagde, S.R.,Mathews, I.I.,Fromme, J.C.,Kim, C.Y. Modular polyketide synthase contains two reaction chambers that operate asynchronously. Science, 374:723-729, 2021 Cited by PubMed: 34735234 DOI: 10.1126/science.abi8532 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation