7PL1

Crystal structure of human METTL1 bound to Sinefungin

Summary for 7PL1

• Entry DOI: 10.2210/pdb7pl1/pdb
• Descriptor: tRNA (guanine-N(7)-)-methyltransferase, GLYCEROL, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: methyltranferase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 30154.36

Authors

Nai, F.,Caflisch, A. (deposition date: 2021-08-27, release date: 2021-09-15, Last modification date: 2023-12-20)

• Primary citation: Nai, F.,Flores Espinoza, M.P.,Invernizzi, A.,Vargas-Rosales, P.A.,Bobileva, O.,Herok, M.,Caflisch, A.; Small-Molecule Inhibitors of the m7G-RNA Writer METTL1; Acs Bio Med Chem Au, 2023; DOI: 10.1021/acsbiomedchemau.3c00030

Experimental method

X-RAY DIFFRACTION (1.85 Å)