7MYZ

Structure of the full length 5-TM receptor CD47 bound to Fab B6H12

Summary for 7MYZ

• Entry DOI: 10.2210/pdb7myz/pdb
• Descriptor: Fusion protein of Leukocyte surface antigen CD47 an Soluble cytochrome b562, B6H12 Fab heavy chain, B6H12 Fab light chain, ... (6 entities in total)
• Functional Keywords: 5-tm receptor, immune receptor, phagocytosis inhibitor, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 188000.08

Authors

Fenalti, G.,Villanueva, N. (deposition date: 2021-05-22, release date: 2021-09-08, Last modification date: 2023-10-18)

• Primary citation: Fenalti, G.,Villanueva, N.,Griffith, M.,Pagarigan, B.,Lakkaraju, S.K.,Huang, R.Y.,Ladygina, N.,Sharma, A.,Mikolon, D.,Abbasian, M.,Johnson, J.,Hadjivassiliou, H.,Zhu, D.,Chamberlain, P.P.,Cho, H.,Hariharan, K.; Structure of the human marker of self 5-transmembrane receptor CD47.; Nat Commun, 12:5218-5218, 2021; PubMed: 34471125; DOI: 10.1038/s41467-021-25475-w

Experimental method

X-RAY DIFFRACTION (3.4 Å)