7MYZ
Structure of the full length 5-TM receptor CD47 bound to Fab B6H12
Summary for 7MYZ
Entry DOI | 10.2210/pdb7myz/pdb |
Descriptor | Fusion protein of Leukocyte surface antigen CD47 an Soluble cytochrome b562, B6H12 Fab heavy chain, B6H12 Fab light chain, ... (6 entities in total) |
Functional Keywords | 5-tm receptor, immune receptor, phagocytosis inhibitor, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 188000.08 |
Authors | Fenalti, G.,Villanueva, N. (deposition date: 2021-05-22, release date: 2021-09-08, Last modification date: 2023-10-18) |
Primary citation | Fenalti, G.,Villanueva, N.,Griffith, M.,Pagarigan, B.,Lakkaraju, S.K.,Huang, R.Y.,Ladygina, N.,Sharma, A.,Mikolon, D.,Abbasian, M.,Johnson, J.,Hadjivassiliou, H.,Zhu, D.,Chamberlain, P.P.,Cho, H.,Hariharan, K. Structure of the human marker of self 5-transmembrane receptor CD47. Nat Commun, 12:5218-5218, 2021 Cited by PubMed: 34471125DOI: 10.1038/s41467-021-25475-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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