7MTX

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P176

Replaces:  5URR

Summary for 7MTX

• Entry DOI: 10.2210/pdb7mtx/pdb
• Related: 3TSB 3TSD 3USB 4MJM 4MY1 4MY8 4MY9 4MYA 4MYX 4QM1 5URS 7MTU
• Descriptor: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-beta-D-ribopyranosylamine, ... (5 entities in total)
• Functional Keywords: impdh, tim barrel, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex
• Biological source: Bacillus anthracis; More
• Total number of polymer chains: 8
• Total formula weight: 332582.74

Authors

Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-05-13, release date: 2021-06-09, Last modification date: 2023-10-18)

• Primary citation: Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P176; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.44 Å)