7MTX
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P176
Replaces: 5URRSummary for 7MTX
Entry DOI | 10.2210/pdb7mtx/pdb |
Related | 3TSB 3TSD 3USB 4MJM 4MY1 4MY8 4MY9 4MYA 4MYX 4QM1 5URS 7MTU |
Descriptor | Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-beta-D-ribopyranosylamine, ... (5 entities in total) |
Functional Keywords | impdh, tim barrel, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex |
Biological source | Bacillus anthracis More |
Total number of polymer chains | 8 |
Total formula weight | 332582.74 |
Authors | Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-05-13, release date: 2021-06-09, Last modification date: 2023-10-18) |
Primary citation | Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P176 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.44 Å) |
Structure validation
Download full validation report