7MTU

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P221

Replaces:  5UUW

Summary for 7MTU

• Entry DOI: 10.2210/pdb7mtu/pdb
• Related: 3TSB 3TSD 3USB 4MJM 4MY9 4MYA 4QM1 5URR 5URS 5UUV 5UUZ
• Descriptor: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, GLYCEROL, ... (7 entities in total)
• Functional Keywords: impdh, tim barrel, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Bacillus anthracis; More
• Total number of polymer chains: 8
• Total formula weight: 333236.47

Authors

Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-05-13, release date: 2021-06-09, Last modification date: 2023-10-18)

• Primary citation: Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P221; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.34 Å)