4MYA

Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor A110

Summary for 4MYA

• Entry DOI: 10.2210/pdb4mya/pdb
• Related: 3STB 3STD 3SUB 4MJM 4MXS 4MY1 4MY8 4MY9
• Descriptor: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, 4-{(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy}quinolin-2(1H)-one, ... (5 entities in total)
• Functional Keywords: structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, tim barrel, alpha-beta structure, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Bacillus anthracis (anthrax,anthrax bacterium); More
• Total number of polymer chains: 2
• Total formula weight: 83125.44

Authors

Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Gorla, S.K.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,CSGID,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2013-09-27, release date: 2014-01-01, Last modification date: 2023-09-20)

• Primary citation: Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Anderson, W.F.,Joachimiak, A.; Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor A110; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8997 Å)