3STD
SCYTALONE DEHYDRATASE AND CYANOCINNOLINE INHIBITOR
Summary for 3STD
| Entry DOI | 10.2210/pdb3std/pdb |
| Descriptor | PROTEIN (SCYTALONE DEHYDRATASE), 4-(3,3-diphenylpropylamino)cinnoline-3-carbonitrile, CALCIUM ION, ... (4 entities in total) |
| Functional Keywords | dehydratase, fungal melanin, ec 4.2.1.94, lyase |
| Biological source | Magnaporthe grisea |
| Total number of polymer chains | 3 |
| Total formula weight | 59694.76 |
| Authors | Chen, J.M.,Xu, S.L.,Wawrzak, Z.,Basarab, G.S.,Jordan, D.B. (deposition date: 1998-10-16, release date: 1999-10-16, Last modification date: 2023-09-13) |
| Primary citation | Chen, J.M.,Xu, S.L.,Wawrzak, Z.,Basarab, G.S.,Jordan, D.B. Structure-based design of potent inhibitors of scytalone dehydratase: displacement of a water molecule from the active site. Biochemistry, 37:17735-17744, 1998 Cited by PubMed: 9922139DOI: 10.1021/bi981848r PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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