4MY8

Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor Q21

Summary for 4MY8

• Entry DOI: 10.2210/pdb4my8/pdb
• Related: 3MJM 3MXS 3MY1 3TSB 3TSD 3USB
• Descriptor: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, (2S)-2-(naphthalen-1-yloxy)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]propanamide, ... (7 entities in total)
• Functional Keywords: structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, tim barrel, alpha-beta structure, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Bacillus anthracis (anthrax,anthrax bacterium); More
• Total number of polymer chains: 4
• Total formula weight: 166729.58

Authors

Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Gorla, S.K.,Kavitha, M.,Cuny, G.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,CSGID,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2013-09-27, release date: 2013-11-13, Last modification date: 2023-09-20)

• Primary citation: Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Gorla, S.K.,Kavitha, M.,Cuny, G.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.; Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor Q21; To be Published, 2013

Experimental method

X-RAY DIFFRACTION (2.2924 Å)